SCHEMBL3869213

SCHEMBL3869213

Cc1sc(-c2ccccc2)nc1C1=C(c2sc3ccc(-c4ccccc4)cc3c2C)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ROCK1 Q13464 7/20 0.48
▸ RARA P10276 3/20 0.40
▸ RARB P10826 3/20 0.40
▸ RARG P13631 3/20 0.40
▸ APEX1 P27695 1/20 0.39
▸ ATP4A P20648 2/20 0.35
▸ ATP4B P51164 2/20 0.35
▸ ALOX5 P09917 1/20 0.32
▸ PTGS2 P35354 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ LIMK1 P53667 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3869752 0.92 RARA (0.40) ROCK1RARARARBRARGAPEX1
SCHEMBL3872932 0.92 ROCK1 (0.39) ROCK1RARARARBRARGAPEX1
SCHEMBL3869530 0.89 RARA (0.40) ROCK1RARARARBRARGAPEX1
SCHEMBL3877999 0.86 RARA (0.40) ROCK1RARARARBRARGAPEX1
SCHEMBL3879140 0.85 RARA (0.37) ROCK1RARARARBRARGAPEX1
SCHEMBL3434571 0.82 RARA (0.51) RARARARBRARGAPEX1ATP4A
SCHEMBL3870600 0.80 RARA (0.40) RARARARBRARGAPEX1ATP4A
SCHEMBL3869807 0.78 RARA (0.41) RARARARBRARGAPEX1ATP4A
SCHEMBL3880148 0.78 RARA (0.38) RARARARBRARGAPEX1ATP4A
SCHEMBL3872128 0.77 RARA (0.41) RARARARBRARGAPEX1ATP4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11609442-B2 System and method for customization of a photochromic article TRANSITIONS OPTICAL, LTD. (IE) 2023-03-21 — — US disclosed
US-20210055575-A1 System and Method for Customization of a Photochromic Article TRANSITIONS OPTICAL, LTD. (IE) 2021-02-25 — — US disclosed
EP-3732533-A1 SYSTEM AND METHOD FOR CUSTOMIZATION OF A PHOTOCHROMIC ARTICLE Transitions Optical, Ltd. (IE) 2020-11-04 — — EP disclosed
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 — — US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 — — US disclosed
EP-1637570-B1 Color-memorizing photochromic writing instrument PILOT INK CO LTD (JP) 2007-06-27 — — EP disclosed
CN-1315555-C Method of alternatively dioplaying photochromic action of memory color in toy assembly, and photochromic toy having alternatively color memory PILOT INK CO LTD (JP) 2007-05-16 — — CN disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 — — US disclosed
EP-1637570-A1 Color-memorizing photochromic writing instrument THE PILOT INK CO., LTD. (JP) 2006-03-22 — — EP disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 — — US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 — — EP disclosed
US-20040135097-A1 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. 2004-07-15 — — US disclosed
CN-1498666-A Method of alternatively dioplaying photochromic action of memory color in toy assembly, and photochromic toy having alternatively color memory ��ī�����˹��ʽ���� 2004-05-26 — — CN disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 — — EP disclosed
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