SCHEMBL3879140

SCHEMBL3879140

Cc1ccc2c(C)c(C3=C(c4nc(-c5ccccc5)sc4C)C(F)(F)C(F)(F)C3(F)F)sc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RARA P10276 2/20 0.37
▸ RARB P10826 2/20 0.37
▸ RARG P13631 2/20 0.37
▸ APEX1 P27695 1/20 0.37
▸ ALOX5 P09917 1/20 0.34
▸ APP P05067 4/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ ATP4A P20648 2/20 0.33
▸ ATP4B P51164 2/20 0.33
▸ ROCK1 Q13464 1/20 0.33
▸ GLA P06280 2/20 0.32
▸ MAPT P10636 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ MAPK14 Q16539 1/20 0.31
▸ DHODH Q02127 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3872932 0.92 ROCK1 (0.39) RARARARBRARGAPEX1ALOX5
SCHEMBL3869752 0.92 RARA (0.40) RARARARBRARGAPEX1ALOX5
SCHEMBL3869530 0.89 RARA (0.40) RARARARBRARGAPEX1ALOX5
SCHEMBL3870541 0.86 RARA (0.38) RARARARBRARGAPEX1ALOX5
SCHEMBL3869213 0.85 ROCK1 (0.48) RARARARBRARGAPEX1ALOX5
SCHEMBL3434571 0.82 RARA (0.51) RARARARBRARGAPEX1ALOX5
SCHEMBL3880148 0.80 RARA (0.38) RARARARBRARGAPEX1ALOX5
SCHEMBL3869807 0.78 RARA (0.41) RARARARBRARGAPEX1ALOX5
SCHEMBL3870600 0.78 RARA (0.40) RARARARBRARGAPEX1ALOX5
SCHEMBL3872128 0.75 RARA (0.41) RARARARBRARGAPEX1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11609442-B2 System and method for customization of a photochromic article TRANSITIONS OPTICAL, LTD. (IE) 2023-03-21 — — US disclosed
US-20210055575-A1 System and Method for Customization of a Photochromic Article TRANSITIONS OPTICAL, LTD. (IE) 2021-02-25 — — US disclosed
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 — — US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 — — US disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 — — US disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 — — US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 — — EP disclosed
US-20040135097-A1 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. 2004-07-15 — — US disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 — — EP disclosed
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