Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30045078 | 1.00 | TSHR (0.60) | TSHRPTGS1AKR1C3MEN1KMT2A | |
| SCHEMBL29890128 | 1.00 | TSHR (0.60) | TSHRPTGS1AKR1C3MEN1KMT2A | |
| SCHEMBL192456 | 1.00 | TSHR (0.60) | TSHRPTGS1AKR1C3MEN1KMT2A | |
| SCHEMBL1677135 | 1.00 | TSHR (0.60) | TSHRPTGS1AKR1C3MEN1KMT2A | |
| Alcohol SCHEMBL9863179 | 0.92 | TSHR (0.51) | TSHRPTGS1AKR1C3MEN1KMT2A | |
| SCHEMBL11424402 | 0.89 | TSHR (0.47) | TSHRPTGS1AKR1C3MEN1KMT2A | |
| SCHEMBL359346 | 0.87 | TSHR (0.44) | TSHRPTGS1AKR1C3MEN1KMT2A | |
| SCHEMBL10507535 | 0.87 | TSHR (0.44) | TSHRPTGS1AKR1C3MEN1KMT2A | |
| SCHEMBL5394591 | 0.87 | TSHR (0.44) | TSHRPTGS1AKR1C3MEN1KMT2A | |
| SCHEMBL11248942 | 0.87 | TSHR (0.44) | TSHRPTGS1AKR1C3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560585-B2 | Process for preparing (S)- alpha-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)-isovalerate | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-07-14 | — | — | US | claimed |
| US-20060128982-A1 | Process for preparing (S)- alpha-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)-isovalerate | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2006-06-15 | — | — | US | claimed |
| WO-2006010994-A1 | PROCESS FOR PREPARING (S)-ALPHA-CYANO-3-PHENOXYBENZYL-(S)-2-(4-CHLOROPHENYL)-ISOVALERATE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-02-02 | — | — | WO | claimed |
| EP-0132392-B1 | ASYMMETRIC SYNTHESIS OF ALPHA-SUBSTITUTED-ALPHA-CYANOMETHYL ALCOHOLS | ICI AUSTRALIA LIMITED (AU) | 1992-01-02 | — | — | EP | claimed |
| US-4985365-A | WITH AN ESTERASE FROM A MICROORGANISM, ASSYMETRIC HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1991-01-15 | — | — | US | claimed |
| EP-0080827-B1 | METHOD FOR BIOTECHNOLOGICALLY PREPARING (S)-(-)-ALPHA-CYANO-3-PHENOXYBENZYL ALCOHOL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-09 | — | — | EP | claimed |
| US-4701542-A | Resolution of hemiacetals and alcohols | ROUSSEL UCLAF (FR) | 1987-10-20 | — | — | US | claimed |
| EP-0082049-B1 | ETHERS WITH CHIRAL ATOMS IN THE ORGANIC REST GROUPS, THEIR PREPARATION, THEIR USE IN THE RESOLUTION OF ALCOHOLS OR OF CERTAIN HEMIACETALS, AND COMPOUNDS SO RESOLVED | ROUSSEL-UCLAF (FR) | 1987-07-29 | — | — | EP | claimed |
| EP-0095794-B1 | ESTERS OF 2,2-DIMETHYL-3-FORMYL-1-CYCLOPROPANE-CARBOXYLIC ACID | ROUSSEL-UCLAF (FR) | 1985-09-18 | — | — | EP | claimed |
| EP-0132392-A2 | Asymmetric synthesis of alpha-substituted-alpha-cyanomethyl alcohols | ICI AUSTRALIA LIMITED (AU) | 1985-01-30 | — | — | EP | claimed |
| EP-0030887-B1 | IMINES DERIVED FROM ESTERS OF 3-FORMYL-CYCLOPROPANE-1-CARBOXYLIC ACIDS, THEIR PREPARATIONS, THEIR USE IN THE PREPARATION OF CORRESPONDING 3-VINYL-SUBSTITUTED ESTERS | ROUSSEL-UCLAF (FR) | 1984-01-18 | — | — | EP | claimed |
| EP-0007255-B1 | SUBSTITUTED CYCLOPROPANE CARBOXYLIC ACID ESTERS OF ALPHA-CYANATED ALCOHOLS, A PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS CONTAINING THEM, AS WELL AS THEIR USE AS VETERINARY MEDICAMENTS | ROUSSEL-UCLAF (FR) | 1983-07-06 | — | — | EP | claimed |
| EP-0080827-A2 | Method for biotechnologically preparing (S)-(-)-alpha-cyano-3-phenoxybenzyl alcohol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-08 | — | — | EP | claimed |
| US-4344895-A | ESTERIFICATION, HYDROLYSIS | ROUSSEL UCLAF (FR) | 1982-08-17 | — | — | US | claimed |
| US-4312817-A | Imino derivatives | ROUSSEL UCLAF (FR) | 1982-01-26 | — | — | US | claimed |
| US-4151195-A | Novel racemization process | ROUSSEL UCLAF (FR) | 1979-04-24 | — | — | US | claimed |
| JP-58212790-A | — | — | None | — | — | JP | disclosed |
| JP-2049759-A | — | — | None | — | — | JP | disclosed |
| US-4133826-A | REACTION OF OPTICALLY ACTIVE OR RACEMIC MIXTURE OF ESTERS WITH BASE | ROUSSEL UCLAF (FR) | 1979-01-09 | — | — | US | disclosed |
| JP-S05894389-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128982-A1 | Process for preparing (S)- alpha-cyano-3-phenoxybenzyl-(S)-2-(4-chlorophenyl)-isovalerate | PCCA, CHRNE, CHRNB4 | TSHR 3108/4885PTGS1 4013/4885AKR1C3 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.