Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249733 | 0.89 | TSHR (0.46) | TSHRCCR1ARPTGS1ADRB3 | |
| SCHEMBL1677135 | 0.87 | TSHR (0.60) | TSHRCCR1PTGS1MEN1CYP2D6 | |
| SCHEMBL30045078 | 0.87 | TSHR (0.60) | TSHRCCR1PTGS1MEN1CYP2D6 | |
| SCHEMBL192456 | 0.87 | TSHR (0.60) | TSHRCCR1PTGS1MEN1CYP2D6 | |
| SCHEMBL3880467 | 0.87 | TSHR (0.60) | TSHRCCR1PTGS1MEN1CYP2D6 | |
| SCHEMBL29890128 | 0.87 | TSHR (0.60) | TSHRCCR1PTGS1MEN1CYP2D6 | |
| SCHEMBL5394591 | 0.85 | TSHR (0.44) | TSHRPTGS1MEN1CYP2D6KMT2A | |
| SCHEMBL10507535 | 0.85 | TSHR (0.44) | TSHRPTGS1MEN1CYP2D6KMT2A | |
| SCHEMBL11233625 | 0.85 | TSHR (0.44) | TSHRARPTGS1MEN1CYP2D6 | |
| SCHEMBL11142983 | 0.85 | PTGS1 (0.44) | CCR1PPARGPPARAPTGS1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792889-B1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2015-03-04 | — | — | EP | disclosed |
| CN-102365264-B | Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof | SUMITOMO CHEMICAL CO | 2014-05-21 | — | — | CN | disclosed |
| EP-2418197-B1 | PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF | SUMITOMO CHEMICAL CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-1547995-B1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8461370-B2 | Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-11 | — | — | US | disclosed |
| EP-2537828-A1 | METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT | Sumitomo Chemical Company, Limited (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-20120310003-A1 | METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-06 | — | — | US | disclosed |
| WO-2012150206-A2 | NOVEL CYCLOPROPANOIC ACID ESTER DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012150207-A1 | USE OF CYCLOPROPANECARBOXYLIC ACID ESTER DERIVATIVES FOR CONTROLLING INSECTICIDE-RESISTANT INSECTS | BAYER CROPSCIENCE AG (DE) | 2012-11-08 | — | — | WO | disclosed |
| CN-102762532-A | Method for producing cyanoalkenylcyclopropanecarboxylic acid salt | SUMITOMO CHEMICAL CO | 2012-10-31 | — | — | CN | disclosed |
| EP-0992479-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-04-12 | — | — | EP | disclosed |
| EP-0104908-B1 | ARTHROPODICIDAL COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1990-12-27 | — | — | EP | disclosed |
| US-4849450-A | INSECTICIDES, MITICIDES | DUNLENA PTY. LTD. (AU) | 1989-07-18 | — | — | US | disclosed |
| EP-0118283-B1 | PHENYL-CYCLOBUTANE CARBOXYLATES AS ARTHROPODICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1988-11-02 | — | — | EP | disclosed |
| EP-0091208-B1 | METHOD FOR COMBATING INSECT PESTS, AND NOVEL CYCLOPROPANE CARBOXYLATES USEFUL AS ACTIVE INGREDIENTS THEREIN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-06-18 | — | — | EP | disclosed |
| EP-0118283-A1 | Phenyl-cyclobutane carboxylates as arthropodicides | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1984-09-12 | — | — | EP | disclosed |
| EP-0104908-A1 | Arthropodicidal compounds | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1984-04-04 | — | — | EP | disclosed |
| EP-0091208-A1 | Method for combating insect pests, and novel cyclopropane carboxylates useful as active ingredients therein | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-10-12 | — | — | EP | disclosed |
| US-4390715-A | INSECTICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1983-06-28 | — | — | US | disclosed |
| EP-0044718-A2 | Pesticidal pentafluorobenzyl esters of cycloalkyl carboxylic acids | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1982-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120310003-A1 | METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT | MCCC2, AOC2, DDC | TSHR 1331/4885CCR1 140/4885AR 3761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.