Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617475 | 0.92 | PPARA (0.48) | FOLH1PPARAPPARGMEN1GAA | |
| SCHEMBL2564729 | 0.92 | PPARA (0.48) | FOLH1PPARAPPARGMEN1GAA | |
| SCHEMBL617476 | 0.92 | PPARA (0.48) | FOLH1PPARAPPARGMEN1GAA | |
| SCHEMBL6337223 | 0.87 | PPARA (0.47) | FOLH1PPARAPPARGMEN1GAA | |
| SCHEMBL2323692 | 0.87 | PPARA (0.47) | FOLH1PPARAPPARGMEN1GAA | |
| SCHEMBL384624 | 0.87 | PPARA (0.47) | FOLH1PPARAPPARGMEN1GAA | |
| SCHEMBL4371936 | 0.87 | FOLH1 (0.43) | FOLH1PPARAPPARGRIMKLANAALAD2 | |
| SCHEMBL29454915 | 0.86 | CTSK (0.50) | PPARAPPARGMEN1GAAKMT2A | |
| SCHEMBL17637824 | 0.85 | MAPT (0.46) | FOLH1RIMKLANAALAD2MEN1GAA | |
| SCHEMBL19365108 | 0.85 | MAPT (0.46) | FOLH1RIMKLANAALAD2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7479371-B2 | Method of judging leukemia, pre-leukemia or aleukemic malignant blood disease and diagnostic therefor | TOKAI UNIVERSITY (JP) | 2009-01-20 | — | — | US | disclosed |
| US-20060084122-A1 | Method of judging leukemia, pre-leukemia or aleukemic malignant blood disease and diagnostic therefor | KYOWA MEDEX CO., LTD. (25%) (JP) | 2006-04-20 | — | — | US | disclosed |
| EP-1496360-A1 | METHOD OF JUDGING LEUKEMIA, PRE-LEUKEMIA OR ALEUKEMIC MALIGNANT BLOOD DISEASE AND DIAGNOSTIC THEREFOR | TOKAI UNIVERSITY (JP) | 2005-01-12 | — | — | EP | disclosed |
| CN-1243505-A | Benzamidine derivatives | AJINOMOTO KK (JP) | 2000-02-02 | — | — | CN | disclosed |