SCHEMBL384624

SCHEMBL384624

COC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 9/20 0.47
PPARG P37231 8/20 0.47
CTSK P43235 6/20 0.47
CTSS P25774 5/20 0.47
ACE P12821 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.46
PPARD Q03181 2/20 0.45
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43
FOLH1 Q04609 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2323692 1.00 PPARA (0.47) PPARAPPARGCTSKCTSSACE
SCHEMBL6337223 1.00 PPARA (0.47) PPARAPPARGCTSKCTSSACE
Benzene SCHEMBL28847299 0.97 PPARA (0.51) PPARAPPARGCTSKCTSSACE
SCHEMBL617475 0.92 PPARA (0.48) PPARAPPARGCTSKCTSSACE
SCHEMBL2564729 0.92 PPARA (0.48) PPARAPPARGCTSKCTSSACE
SCHEMBL617476 0.92 PPARA (0.48) PPARAPPARGCTSKCTSSACE
SCHEMBL2726974 0.91 CTSK (0.51) PPARAPPARGCTSKCTSSACE
SCHEMBL211798 0.91 CTSK (0.51) PPARAPPARGCTSKCTSSACE
SCHEMBL211797 0.91 CTSK (0.51) PPARAPPARGCTSKCTSSACE
SCHEMBL22283971 0.90 CTSK (0.46) PPARAPPARGCTSKCTSSACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473291-B2 Benzodiazepine compound, preparation method therefor, and use thereof in medicine WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) 2025-11-18 US claimed
CN-115068624-B Peptide dendrimer drug-carrying system and preparation method and application thereof 重庆理工大学 2024-02-13 CN claimed
US-20220324867-A1 BENZODIAZEPINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) 2022-10-13 US claimed
CN-115068624-A Peptide dendrimer drug-carrying system and preparation method and application thereof 重庆理工大学 2022-09-20 CN claimed
CN-105431135-A Polymeric drug delivery system for treating surgical complications TYRX INC 2016-03-23 CN claimed
CN-102458640-A Multi-phase microparticles and method for producing multi-phase microparticles UNIV NANYANG TECH 2012-05-16 CN claimed
EP-0145875-A2 Gamma-aminobutyric acid transaminase inhibitors and processes for their preparation MERRELL DOW PHARMACEUTICALS INC. (US) 1985-06-26 EP claimed
US-12605459-B2 Protein-drug conjugates comprising camptothecin analogs and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2026-04-21 US disclosed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
EP-4711368-A1 AZEPINE COMPOUND, AND COMPOSITION AND USE THEREOF CHENGDU MFS PHARMA. CO., LTD. (CN) 2026-03-18 EP disclosed
US-20260061065-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2026-03-05 US disclosed
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2025-12-25 US disclosed
US-20250367332-A1 PSMA-TARGETED RADIOACTIVE METAL COMPLEX CONTAINING NITROAROMATIC HETEROCYCLIC GROUP AND PREPARATION METHOD UNIV BEIJING NORMAL (CN) 2025-12-04 US disclosed
US-5075099-A Metal radionuclide chelating compounds for improved chelation kinetics NEORX CORPORATION (US) 1991-12-24 US disclosed
US-4988496-A Metal radionuclide chelating compounds for improved chelation kinetics NEORX CORPORATION (US) 1991-01-29 US disclosed
EP-0344724-A2 Metal radionuclide chelating compounds for improved chelation kinetics NEORX CORPORATION (US) 1989-12-06 EP disclosed
EP-0329481-A2 Anchimeric radiometal chelating compounds NEORX CORPORATION (US) 1989-08-23 EP disclosed
US-4824974-A Synthesis for the preparation of 4-amino-4,5-dihydro-2-furancarboxylic acid MERRELL DOW PHARMACEUTICALS INC. (US) 1989-04-25 US disclosed
US-4588825-A Intermediates for the synthesis of 4-amino-4,5-dihydro-2-furancarboxylic acid MERRELL DOW PHARMACEUTICALS INC. (US) 1986-05-13 US disclosed
EP-0145875-A2 Gamma-aminobutyric acid transaminase inhibitors and processes for their preparation MERRELL DOW PHARMACEUTICALS INC. (US) 1985-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220324867-A1 BENZODIAZEPINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE GABRA1, GABRA4, GABRR1 PPARA 1366/4885PPARG 504/4885CTSK 4850/4885
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF BID, BCL2, MCL1 PPARA 3930/4885PPARG 3997/4885CTSK 3327/4885
US-12605459-B2 Protein-drug conjugates comprising camptothecin analogs and methods of use thereof FOLH1, TGM2, SLC3A2 PPARA 4456/4885PPARG 3064/4885CTSK 2554/4885
US-20260061065-A1 ANTIBODY DRUG CONJUGATES FCGR2A, FCGR3B, BCL3 PPARA 3847/4885PPARG 3994/4885CTSK 2216/4885
US-20250367332-A1 PSMA-TARGETED RADIOACTIVE METAL COMPLEX CONTAINING NITROAROMATIC HETEROCYCLIC GROUP AND PREPARATION METHOD PSMA1, PSMA2, PSMA7 PPARA 1925/4885PPARG 2134/4885CTSK 1234/4885
US-12473291-B2 Benzodiazepine compound, preparation method therefor, and use thereof in medicine GABRA1, GABRA4, GABRR1 PPARA 1366/4885PPARG 504/4885CTSK 4850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.