SCHEMBL617476

SCHEMBL617476

CC(C)(C)OC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 8/20 0.48
PPARG P37231 7/20 0.48
CTSK P43235 6/20 0.48
CTSS P25774 5/20 0.48
ACE P12821 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HTT P42858 1/20 0.47
PPARD Q03181 2/20 0.46
CYP2D6 P10635 1/20 0.45
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
FOLH1 Q04609 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2564729 1.00 PPARA (0.48) PPARAPPARGCTSKCTSSACE
SCHEMBL617475 1.00 PPARA (0.48) PPARAPPARGCTSKCTSSACE
SCHEMBL29454915 0.94 CTSK (0.50) PPARAPPARGCTSKCTSSACE
SCHEMBL384624 0.92 PPARA (0.47) PPARAPPARGCTSKCTSSACE
SCHEMBL2323692 0.92 PPARA (0.47) PPARAPPARGCTSKCTSSACE
SCHEMBL6337223 0.92 PPARA (0.47) PPARAPPARGCTSKCTSSACE
SCHEMBL3880876 0.92 FOLH1 (0.42) PPARAPPARGCTSKCTSSACE
SCHEMBL17600320 0.90 CTSK (0.52) PPARAPPARGCTSKCTSSACE
SCHEMBL17600321 0.90 CTSK (0.52) PPARAPPARGCTSKCTSSACE
Benzene SCHEMBL28847299 0.89 PPARA (0.51) PPARAPPARGCTSKCTSSACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4227300-B1 TRUNCATED EVANS BLUE MODIFIED FIBROBLAST ACTIVATION PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF YANTAI LANNACHENG BIOTECHNOLOGY CO LTD (CN) 2026-01-28 EP claimed
CN-114989091-B Preparation method of glutaminyl ethyl imidazole 水羊化妆品制造有限公司 2025-03-21 CN claimed
US-11975079-B2 Truncated Evans Blue modified fibroblast activation protein inhibitor, preparation method and application thereof YANTAI LANNACHENG BIOTECHNOLOGY CO., LTD. (CN) 2024-05-07 US claimed
US-20230390421-A1 TRUNCATED EVANS BLUE MODIFIED FIBROBLAST ACTIVATION PROTEIN INHIBITOR, PREPARATION METHOD AND APPLICATION THEREOF YANTAI LANNACHENG BIOTECHNOLOGY CO., LTD. (CN) 2023-12-07 US claimed
CN-117120428-A Truncated Evan blue modified fibroblast activation protein inhibitor and preparation method and application thereof 烟台蓝纳成生物技术有限公司 2023-11-24 CN claimed
EP-4227300-A1 TRUNCATED EVANS BLUE MODIFIED FIBROBLAST ACTIVATION PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Yantai Lannacheng Biotechnology Co., Ltd. (CN) 2023-08-16 EP claimed
CN-114409607-B Thioether group-containing N-carboxyl cyclic anhydride and preparation method and application thereof 长春理工大学 2023-08-08 CN claimed
CN-116178733-B Branched monodisperse PEG derivative based on trifunctional amino acid, preparation method and application 浙江博美生物技术有限公司 2023-08-01 CN claimed
CN-115260160-B Compound of targeted fibroblast activation protein FAP, preparation method and application thereof 烟台蓝纳成生物技术有限公司 2023-06-20 CN claimed
CN-116178733-A Branched monodisperse PEG derivative based on trifunctional amino acid, preparation method and application 浙江博美生物技术有限公司 2023-05-30 CN claimed
CN-114369084-B Truncated Evans blue modified fibroblast activation protein inhibitor and preparation method and application thereof 烟台蓝纳成生物技术有限公司 2023-02-03 CN claimed
CN-115260278-A Preparation method and application of cryptotanshinone self-assembled prodrug micelle nanoparticles 南方医科大学 2022-11-01 CN claimed
CN-115260160-A Compound of targeted fibroblast activation protein FAP and preparation method and application thereof 烟台蓝纳成生物技术有限公司 2022-11-01 CN claimed
CN-114989091-A Preparation method of glutamyl ethyl imidazole 水羊化妆品制造有限公司 2022-09-02 CN claimed
CN-114369084-A Truncated Evans blue modified fibroblast activation protein inhibitor and preparation method and application thereof 上海蓝纳成生物技术有限公司 2022-04-19 CN claimed
CN-113582975-A Truncated Evans blue modified fibroblast activation protein inhibitor and preparation method and application thereof 上海蓝纳成生物技术有限公司 2021-11-02 CN claimed
CN-106478449-A A kind of γ glutamic acid transferring enzyme fluorescent probe and its preparation and application 浙江工业大学 2017-03-08 CN claimed
CN-122094963-A Cardioprotective lipids and methods of use 2026-05-26 CN disclosed
EP-1028942-A2 DIPEPTIDE NITRILES Novartis AG (CH) 2000-08-23 EP disclosed
WO-1999024460-A2 DIPEPTIDE NITRILES NOVARTIS AG (CH) 1999-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230390421-A1 TRUNCATED EVANS BLUE MODIFIED FIBROBLAST ACTIVATION PROTEIN INHIBITOR, PREPARATION METHOD AND APPLICATION THEREOF FIBP, FAP, ANPEP PPARA 3827/4885PPARG 3385/4885CTSK 815/4885
US-11975079-B2 Truncated Evans Blue modified fibroblast activation protein inhibitor, preparation method and application thereof FIBP, FAP, ANPEP PPARA 3827/4885PPARG 3385/4885CTSK 815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.