SCHEMBL3881579

SCHEMBL3881579

CC1(OC(=O)C2CC3C=CC2C3)C2CC3CC(C2)CC1(O)C3

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
ALDH1A1 P00352 5/20 0.35
EPHX2 P34913 1/20 0.34
POLB P06746 2/20 0.33
APEX1 P27695 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
ESR2 Q92731 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 2/20 0.33
RAB9A P51151 1/20 0.32
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL524854 0.80 KDM4E (0.41) KDM4ELMNAALDH1A1EPHX2POLB
SCHEMBL23187878 0.80 KDM4E (0.41) KDM4ELMNAALDH1A1EPHX2POLB
SCHEMBL1415384 0.78 KDM4E (0.45) KDM4ELMNAALDH1A1EPHX2POLB
SCHEMBL3871919 0.75 KDM4E (0.38) KDM4ELMNAALDH1A1POLBAPEX1
SCHEMBL525636 0.75 KDM4E (0.40) KDM4ELMNAALDH1A1EPHX2POLB
SCHEMBL5025391 0.74 ALDH1A1 (0.41) KDM4ELMNAALDH1A1EPHX2POLB
SCHEMBL7125998 0.73 ALDH1A1 (0.38) KDM4ELMNAALDH1A1EPHX2POLB
SCHEMBL14358509 0.73 SCN1A (0.34) ALDH1A1EPHX2HSD11B1
SCHEMBL3874587 0.71 KDM4E (0.39) KDM4ELMNAALDH1A1EPHX2POLB
SCHEMBL12251466 0.71 KDM4E (0.36) KDM4ELMNAALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090148790-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2009-06-11 US disclosed
US-7521169-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2009-04-21 US disclosed
US-20060234153-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-10-19 US disclosed
EP-1557718-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2005-07-27 EP disclosed