SCHEMBL524854

SCHEMBL524854

CC1(OC(=O)C2CC3C=CC2C3)C2CC3CC(C2)CC1C3

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 6/20 0.38
CYP17A1 P05093 2/20 0.37
CYP19A1 P11511 2/20 0.37
POLB P06746 2/20 0.36
APEX1 P27695 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
ESR2 Q92731 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 2/20 0.36
RAB9A P51151 1/20 0.35
EPHX2 P34913 2/20 0.35
THRB P10828 1/20 0.32
MAPK1 P28482 1/20 0.31
HSD11B1 P28845 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23187878 1.00 KDM4E (0.41) KDM4ELMNAALDH1A1CYP17A1CYP19A1
SCHEMBL12251466 0.87 KDM4E (0.36) KDM4ELMNAALDH1A1POLBAPEX1
SCHEMBL14560632 0.86 ALDH1A1 (0.45) KDM4ELMNAALDH1A1CYP17A1CYP19A1
SCHEMBL22319311 0.85 ALDH1A1 (0.47) KDM4ELMNAALDH1A1CYP17A1CYP19A1
SCHEMBL22263782 0.85 CYP17A1 (0.41) KDM4ELMNAALDH1A1CYP17A1CYP19A1
SCHEMBL525636 0.83 KDM4E (0.40) KDM4ELMNAALDH1A1POLBAPEX1
SCHEMBL22319312 0.82 CYP17A1 (0.37) KDM4ELMNAALDH1A1CYP17A1CYP19A1
SCHEMBL5025391 0.82 ALDH1A1 (0.41) KDM4ELMNAALDH1A1POLBAPEX1
SCHEMBL3881579 0.80 KDM4E (0.37) KDM4ELMNAALDH1A1POLBAPEX1
SCHEMBL721606 0.79 KDM4E (0.36) KDM4ELMNAALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116500858-A Coating of combined photoresist and Si-based hard mask 上海艾深斯科技有限公司 2023-07-28 CN claimed
WO-2021146494-A1 FINE FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE ESTER DERIVATIVES PROMERUS, LLC (US) 2021-07-22 WO claimed
EP-3824054-A2 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES Promerus, LLC (US) 2021-05-26 EP claimed
WO-2020018485-A2 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES PROMERUS, LLC (US) 2020-01-23 WO claimed
US-11970557-B2 Polymer containing photoacid generator LG CHEM, LTD. (KR) 2024-04-30 US disclosed
US-11886119-B2 Material for forming underlayer film, resist underlayer film, method of producing resist underlayer film, and laminate MITSUI CHEMICALS, INC. (JP) 2024-01-30 US disclosed
CN-110709774-B Underlayer film forming material, resist underlayer film, method for producing resist underlayer film, and laminate 三井化学株式会社 2023-12-08 CN disclosed
CN-116500858-A Coating of combined photoresist and Si-based hard mask 上海艾深斯科技有限公司 2023-07-28 CN disclosed
US-20230185195-A1 MATERIAL FOR FORMING UNDERLAYER FILM, RESIST UNDERLAYER FILM, METHOD OF PRODUCING RESIST UNDERLAYER FILM, AND LAMINATE MITSUI CHEMICALS, INC. (JP) 2023-06-15 US disclosed
US-11599025-B2 Resin material for forming underlayer film, resist underlayer film, method of producing resist underlayer film, and laminate MITSUI CHEMICALS, INC. (JP) 2023-03-07 US disclosed
US-11572528-B2 Fragrance compositions containing norbornene derivatives PROMERUS, LLC (US) 2023-02-07 US disclosed
US-11549080-B2 Fine fragrance compositions containing norbornene ester derivatives PROMERUS, LLC (US) 2023-01-10 US disclosed
US-20010033987-A1 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-10-25 US disclosed
EP-1143299-A1 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-10-10 EP disclosed
US-20010024763-A1 Photosensitive polymer including copolymer of alkyl vinyl ether and resist composition containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2001-09-27 US disclosed
EP-1128212-A2 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-29 EP disclosed
EP-1125917-A1 Alkyladamantyl esters and their preparation Chem Search Corporation (KR) 2001-08-22 EP disclosed
EP-1120689-A2 Photosensitive copolymers of alkyl vinyl ether and resist compositions containing the same SAMSUNG ELECTRONICS CO. LTD. (KR) 2001-08-01 EP disclosed
US-6222061-B1 FOR PREPARING FLAME RETARDANTS CHEM SEARCH CORP. (KR) 2001-04-24 US disclosed
EP-1041442-A1 Chemical amplification type positive resist SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572528-B2 Fragrance compositions containing norbornene derivatives TAS2R1, TAS2R5, TAS1R1 KDM4E 2831/4885LMNA 3636/4885ALDH1A1 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.