Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398916 | 0.92 | RAD52 (0.37) | LMNAPSMD14RAD52NPSR1USP2 | |
| SCHEMBL28349758 | 0.92 | RAD52 (0.37) | LMNAPSMD14RAD52NPSR1USP2 | |
| SCHEMBL398917 | 0.92 | HDAC8 (0.33) | LMNAUSP2SLC6A4 | |
| Sulfuric Acid SCHEMBL1745561 | 0.83 | MEN1 (0.40) | USP2SLC6A4 | |
| Sulfuric Acid SCHEMBL1745559 | 0.78 | USP2 (0.37) | LMNANPSR1USP2SLC6A4 | |
| Sulfuric Acid SCHEMBL1745560 | 0.78 | HDAC8 (0.39) | LMNAUSP2SLC6A4 | |
| SCHEMBL1568886 | 0.75 | HDAC8 (0.37) | LMNAUSP2SLC6A4 | |
| SCHEMBL1005223 | 0.75 | USP2 (0.35) | NPSR1USP2SLC6A4 | |
| Sulfuric Acid SCHEMBL7741793 | 0.75 | USP2 (0.35) | LMNANPSR1USP2SLC6A4 | |
| SCHEMBL28235863 | 0.75 | TSHR (0.47) | USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010135-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | L'Oréal (FR) | 2009-01-07 | — | — | EP | claimed |
| WO-2007080183-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | L'ORÉAL (FR) | 2007-07-19 | — | — | WO | claimed |
| EP-2010135-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | L'Oréal (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007080183-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | L'ORÉAL (FR) | 2007-07-19 | — | — | WO | disclosed |