Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094690 | 1.00 | CYP19A1 (0.53) | CYP19A1CES1ALDH1A1KDM4EMAPT | |
| SCHEMBL30707960 | 1.00 | CYP19A1 (0.53) | CYP19A1CES1ALDH1A1KDM4EMAPT | |
| SCHEMBL15291325 | 0.88 | CYP2A6 (0.52) | CYP19A1CES1ALDH1A1KDM4EMAPT | |
| SCHEMBL13039620 | 0.81 | DRD2 (0.56) | CYP19A1CES1ACHECYP2A6MAOA | |
| SCHEMBL30737574 | 0.81 | ACHE (0.59) | CYP19A1CES1KDM4EMAPTTSHR | |
| SCHEMBL32679178 | 0.81 | ACHE (0.59) | CYP19A1CES1KDM4EMAPTTSHR | |
| SCHEMBL388171 | 0.81 | ACHE (0.59) | CYP19A1CES1KDM4EMAPTTSHR | |
| SCHEMBL32679177 | 0.81 | ACHE (0.59) | CYP19A1CES1KDM4EMAPTTSHR | |
| SCHEMBL1093558 | 0.81 | ACHE (0.59) | CYP19A1CES1KDM4EMAPTTSHR | |
| SCHEMBL7998826 | 0.81 | ACHE (0.59) | CYP19A1CES1KDM4EMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030147973-A1 | The use of extracts and compounds derived from the plant Aristolochia taliscana and their analogues in the treatment of AIDS. | ACHENBACH HANS (DE) | 2003-08-07 | — | — | US | claimed |
| US-20020099086-A1 | Use of extracts from aristolochia in the treatment of AIDS | PROTEOME SCIENCES PLC | 2002-07-25 | — | — | US | claimed |
| EP-1117415-A1 | USE OF EXTRACTS FROM ARISTOLOCHIA IN THE TREATMENT OF AIDS | PROTEOME SCIENCES PLC (GB) | 2001-07-25 | — | — | EP | claimed |
| EP-1027344-A2 | PHARMACEUTICAL COMPOUNDS ISOLATED FROM ARISTOLOCHIA TALISCANA | PROTEOME SCIENCES PLC (GB) | 2000-08-16 | — | — | EP | claimed |
| WO-2000006182-A1 | USE OF EXTRACTS FROM ARISTOLOCHIA IN THE TREATMENT OF AIDS | PROTEOME SCIENCES, INC. (US) | 2000-02-10 | — | — | WO | claimed |
| WO-1999006388-A2 | PHARMACEUTICAL COMPOUNDS ISOLATED FROM ARISTOLOCHIA TALISCANA | PROTEOME SCIENCES PLC. (GB) | 1999-02-11 | — | — | WO | claimed |
| CN-87104970-A | The amino-5,6,7 that replaces, 8-tetralyl oxo acetate its preparation method and as the purposes of medicine | — | 1988-02-03 | — | — | CN | claimed |
| CN-117242057-A | Process for preparing intermediates useful in the synthesis of sphingosine-1-phosphate receptor agonists | 株式会社LG化学 | 2023-12-15 | — | — | CN | disclosed |
| CN-117177964-A | Novel process for preparing sphingosine-1-phosphate receptor agonists | 株式会社LG化学 | 2023-12-05 | — | — | CN | disclosed |
| CN-110545807-B | Cannabinoid formulations for the treatment of dermatitis and inflammatory skin disorders | 博塔尼克斯制药有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-114222561-A | Alkaline phosphatase formulations and uses thereof | 合成生物制品有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-111328331-A | Compositions and methods for decolonizing antibiotic-resistant bacteria in the intestinal tract | 芬奇治疗公司 | 2020-06-23 | — | — | CN | disclosed |
| CN-111328284-A | Compositions and methods for maintaining and restoring a healthy intestinal barrier | 芬奇治疗公司 | 2020-06-23 | — | — | CN | disclosed |
| US-5149703-A | Anti-asthma, allergen and inflammatory agents, cyctoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-09-22 | — | — | US | disclosed |
| US-5140047-A | Antiinflammatory agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-18 | — | — | US | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |
| US-4886898-A | THROMOBOXANE ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| US-4868332-A | ANTITHROMBOTIC, ANTIATHEROSCLEROTIC, ANTIISCHEMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |
| CN-87107427-A | The aminomethyl-5,6,7 that replaces, 8-naphthane oxo acetate, new midbody product, their preparation process and as the application of medicine | — | 1988-06-22 | — | — | CN | disclosed |
| EP-0270929-A2 | Substituted aminomethyl-5,6,7,8-tetrahydronaphthyl-oxy-acetic acids, intermediate products, process for their preparation and their use in pharmaceuticals | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099086-A1 | Use of extracts from aristolochia in the treatment of AIDS | ATL3, APRT, LSS | CYP19A1 374/4885CES1 1201/4885ALDH1A1 1193/4885 |
| US-20030147973-A1 | The use of extracts and compounds derived from the plant Aristolochia taliscana and their analogues in the treatment of AIDS. | ATL3, ERG28, LSS | CYP19A1 630/4885CES1 1299/4885ALDH1A1 1907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.