Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882109 | 0.89 | PTGS2 (0.41) | PTGS2ENPP2 | |
| SCHEMBL3882740 | 0.89 | AKR1C3 (0.36) | PTGER1PTGER4PTGER3PTGER2PLA2G10 | |
| SCHEMBL3884624 | 0.89 | PTGS2 (0.40) | PTGS2ENPP2 | |
| SCHEMBL3883918 | 0.87 | TRPA1 (0.38) | — | |
| SCHEMBL3882470 | 0.87 | PTGS2 (0.41) | PTGS2ENPP2METPTGER1PTGER4 | |
| SCHEMBL3884996 | 0.87 | ENPP2 (0.38) | PTGS2ENPP2ABCB1NPC1F7 | |
| SCHEMBL3884991 | 0.87 | ENPP2 (0.38) | PTGS2ENPP2ABCB1NPC1F7 | |
| SCHEMBL3881970 | 0.85 | ENPP2 (0.36) | PTGS2ENPP2ABCB1VCP | |
| SCHEMBL3895740 | 0.84 | PTGS2 (0.43) | PTGS2ENPP2METPTGER1PTGER4 | |
| SCHEMBL3884939 | 0.84 | CHRNA7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |