Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881634 | 0.91 | CCNC (0.45) | THRATHRBCCNCCDK8HDAC1 | |
| SCHEMBL3885715 | 0.90 | FFAR4 (0.43) | FFAR4CCNCCDK8HDAC1XDH | |
| SCHEMBL3883891 | 0.88 | XDH (0.39) | THRATHRBHDAC1XDHAKR1C3 | |
| SCHEMBL3885728 | 0.87 | FFAR1 (0.48) | FFAR4CCNCCDK8HDAC1FFAR1 | |
| SCHEMBL3885654 | 0.87 | FFAR4 (0.41) | THRATHRBFFAR4CCNCCDK8 | |
| SCHEMBL3885405 | 0.86 | FFAR1 (0.46) | THRATHRBFFAR4CCNCCDK8 | |
| SCHEMBL3682322 | 0.85 | FFAR4 (0.47) | FFAR4CCNCCDK8HDAC1FFAR1 | |
| SCHEMBL3882770 | 0.84 | FFAR4 (0.40) | FFAR4CCNCCDK8HDAC1FFAR1 | |
| SCHEMBL3882491 | 0.84 | THRA (0.53) | THRATHRBFFAR4CCNCCDK8 | |
| SCHEMBL3885022 | 0.84 | FFAR1 (0.49) | FFAR4CCNCCDK8HDAC1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |