Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893514 | 0.91 | CCNC (0.46) | FFAR1CCNCCDK8CYP19A1CYP11B1 | |
| SCHEMBL3885405 | 0.89 | FFAR1 (0.46) | FFAR1FFAR4CCNCCDK8PTGES | |
| SCHEMBL3882034 | 0.87 | THRA (0.49) | FFAR1FFAR4CCNCCDK8HDAC1 | |
| SCHEMBL3994447 | 0.86 | PTGES (0.43) | FFAR1FFAR4CCNCCDK8CYP11B1 | |
| SCHEMBL3895497 | 0.86 | FFAR4 (0.46) | FFAR1FFAR4CCNCCDK8HDAC1 | |
| SCHEMBL3885151 | 0.86 | PPARG (0.38) | HDAC1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3682322 | 0.85 | FFAR4 (0.47) | FFAR1FFAR4CCNCCDK8CYP1A2 | |
| SCHEMBL27627098 | 0.85 | CCNC (0.46) | CCNCCDK8CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3885715 | 0.85 | FFAR4 (0.43) | FFAR1FFAR4CCNCCDK8HDAC1 | |
| SCHEMBL3882770 | 0.85 | FFAR4 (0.40) | FFAR1FFAR4CCNCCDK8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |