Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 6/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 6/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 3/20 | 0.34 |
| ▸ | CASP6 | P55212 | 2/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476301 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL932859 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL30614595 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| Methane SCHEMBL28294512 | 0.98 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL25256110 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL25217371 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL25256112 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL30352814 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL27815646 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10MAPK10 | |
| SCHEMBL4716290 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110885325-B | Preparation method of (S) -glycidol phthalimide | 新发药业有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-110885325-A | Preparation method of (S) -glycidol phthalimide | 新发药业有限公司 | 2020-03-17 | — | — | CN | disclosed |
| EP-1564215-B1 | Process for preparing glycidylphthalimide | DAISO CO LTD (JP) | 2009-01-07 | — | — | EP | disclosed |
| EP-1619183-B1 | 1-amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1, 4-benzodioxane derivatives | DAISO CO LTD (JP) | 2008-10-01 | — | — | EP | disclosed |
| US-7368608-B2 | 1-amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1,4-benzodioxane derivatives | DAISO CO., LTD. (JP) | 2008-05-06 | — | — | US | disclosed |
| US-7135576-B2 | Process for preparing glycidylphthalimide | DAISO CO., LTD. (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20060019993-A1 | 1-Amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1,4-benzodioxane derivatives | DAISO CO., LTD. (JP) | 2006-01-26 | — | — | US | disclosed |
| EP-1619183-A2 | 1-amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1, 4-benzodioxane derivatives | DAISO CO., LTD. (JP) | 2006-01-25 | — | — | EP | disclosed |
| EP-1403267-B1 | Process for preparing glycidylphthalimide | DAISO CO LTD (JP) | 2006-01-11 | — | — | EP | disclosed |
| EP-1564215-A1 | Process for preparing glycidylphthalimide | DAISO CO., LTD. (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-20050113583-A1 | Process for preparing glycidylphthalimide | OSAKA SODA CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| US-6875875-B2 | Process for preparing glycidylphthalimide | DAISO CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |
| US-20040087802-A1 | Process for preparing glycidylphthalimide | OSAKA SODA CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1403267-A1 | Process for preparing glycidylphthalimide | DAISO CO., LTD. (JP) | 2004-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019993-A1 | 1-Amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1,4-benzodioxane derivatives | CCNL2, CCNA1, CCNK | KDM4E 2478/4885ALDH1A1 438/4885HPGD 257/4885 |
| US-20050113583-A1 | Process for preparing glycidylphthalimide | EZH1, ALKBH3, PHF2 | KDM4E 694/4885ALDH1A1 1435/4885HPGD 1441/4885 |
| US-20040087802-A1 | Process for preparing glycidylphthalimide | EZH1, ALKBH3, PHF2 | KDM4E 694/4885ALDH1A1 1435/4885HPGD 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.