SCHEMBL932859

SCHEMBL932859

O=C1NC(=O)c2c(C[C@H]3CO3)cccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 0.40
▸ ALDH1A1 P00352 6/20 0.40
▸ HPGD P15428 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ MAPK10 P53779 1/20 0.40
▸ GSK3B P49841 2/20 0.38
▸ GAA P10253 2/20 0.38
▸ PARP1 P09874 6/20 0.37
▸ GSK3A P49840 1/20 0.36
▸ CDK5 Q00535 1/20 0.36
▸ CDK5R1 Q15078 1/20 0.36
▸ CASP3 P42574 6/20 0.36
▸ PARP2 Q9UGN5 1/20 0.34
▸ PARP3 Q9Y6F1 1/20 0.34
▸ CASP7 P55210 3/20 0.34
▸ CASP6 P55212 2/20 0.34
▸ CASP8 Q14790 2/20 0.34
▸ CASP2 P42575 1/20 0.34
▸ MEN1 O00255 3/20 0.33
▸ POLB P06746 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3882337 1.00 KDM4E (0.40) KDM4EALDH1A1HPGDHSD17B10MAPK10
SCHEMBL476301 1.00 KDM4E (0.40) KDM4EALDH1A1HPGDHSD17B10MAPK10
SCHEMBL30614595 1.00 KDM4E (0.40) KDM4EALDH1A1HPGDHSD17B10MAPK10
Methane SCHEMBL28294512 0.98 KDM4E (0.40) KDM4EALDH1A1HPGDHSD17B10MAPK10
SCHEMBL25256110 0.88 ALDH1A1 (0.44) KDM4EALDH1A1HPGDHSD17B10MAPK10
SCHEMBL25217371 0.88 ALDH1A1 (0.44) KDM4EALDH1A1HPGDHSD17B10MAPK10
SCHEMBL25256112 0.88 ALDH1A1 (0.44) KDM4EALDH1A1HPGDHSD17B10MAPK10
SCHEMBL30352814 0.88 ALDH1A1 (0.44) KDM4EALDH1A1HPGDHSD17B10MAPK10
SCHEMBL27815646 0.85 KDM4E (0.39) KDM4EALDH1A1HPGDHSD17B10MAPK10
SCHEMBL4716290 0.83 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110885325-B Preparation method of (S) -glycidol phthalimide 新发药业有限公司 2021-09-07 — — CN claimed
US-RE47606-E1 Process for the preparation of linezolid OPTIMUS DRUGS PRIVATE LIMITED (IN) 2019-09-17 — — US claimed
EP-3250568-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF LINEZOLID Optimus Drugs Pvt Ltd (IN) 2017-12-06 — — EP claimed
WO-2017182853-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF LINEZOLID OPTIMUS DRUGS PVT LTD (IN) 2017-10-26 — — WO claimed
US-9643939-B1 Process for the preparation of linezolid OPTIMUS DRUGS PRIVATE LIMITED (US) 2017-05-09 — — US claimed
US-9593104-B2 Process for the preparation of oxazolidinone derivatives BENOVA LABS PVT. LIMITED (IN) 2017-03-14 — — US claimed
US-20160039803-A1 PROCESS FOR THE PREPARATION OF OXAZOLIDINONE DERIVATIVES BENOVA LABS PVT. LIMITED (IN) 2016-02-11 — — US claimed
WO-2014141067-A2 PROCESS FOR THE PREPARATION OF OXAZOLIDINONE DERIVATIVES BENOVA LABS PVT LIMITED (IN) 2014-09-18 — — WO claimed
US-8637667-B2 Method for preparing (S)-5-chloro-N-((3-(4-(5,6-dihydro-4H-1,2,4-oxadiazin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)thiophene-2-carboxamide derivatives LEGOCHEM BIOSCIENCE LTD. (KR) 2014-01-28 — — US claimed
US-20120108808-A1 METHOD FOR PREPARING (S)-5-CHLORO-N-((3-(4-(5,6-DIHYDRO-4H-1,2,4-OXADIAZIN-3-YL)PHENYL)-2-OXOOXAZOLIDIN-5-YL)METHYL)THIOPHENE-2-CARBOXAMIDE DERIVATIVES LEGOCHEM BIOSCIENCE LTD. (KR) 2012-05-03 — — US claimed
US-12503452-B2 Antimicrobial compounds and methods CURZA GLOBAL, LLC (US) 2025-12-23 — — US disclosed
US-20230159491-A1 Antimicrobial Compounds and Methods NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-05-25 — — US disclosed
CN-113924292-A Antimicrobial compounds and methods 库扎环球有限责任公司 2022-01-11 — — CN disclosed
EP-3911644-A1 ANTIMICROBIAL COMPOUNDS AND METHODS Curza Global LLC (US) 2021-11-24 — — EP disclosed
CN-110885325-B Preparation method of (S) -glycidol phthalimide 新发药业有限公司 2021-09-07 — — CN disclosed
EP-1564215-A1 Process for preparing glycidylphthalimide DAISO CO., LTD. (JP) 2005-08-17 — — EP disclosed
US-20050113583-A1 Process for preparing glycidylphthalimide OSAKA SODA CO., LTD. (JP) 2005-05-26 — — US disclosed
US-6875875-B2 Process for preparing glycidylphthalimide DAISO CO., LTD. (JP) 2005-04-05 — — US disclosed
US-20040087802-A1 Process for preparing glycidylphthalimide OSAKA SODA CO., LTD. (JP) 2004-05-06 — — US disclosed
EP-1403267-A1 Process for preparing glycidylphthalimide DAISO CO., LTD. (JP) 2004-03-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159491-A1 Antimicrobial Compounds and Methods MPO, NISCH, RPN2 KDM4E 3027/4885ALDH1A1 3752/4885HPGD 1474/4885
US-20050113583-A1 Process for preparing glycidylphthalimide EZH1, ALKBH3, PHF2 KDM4E 694/4885ALDH1A1 1435/4885HPGD 1441/4885
US-20160039803-A1 PROCESS FOR THE PREPARATION OF OXAZOLIDINONE DERIVATIVES OXA1L, PPOX, AZI2 KDM4E 118/4885ALDH1A1 1330/4885HPGD 1284/4885
US-20040087802-A1 Process for preparing glycidylphthalimide EZH1, ALKBH3, PHF2 KDM4E 694/4885ALDH1A1 1435/4885HPGD 1441/4885
US-20120108808-A1 METHOD FOR PREPARING (S)-5-CHLORO-N-((3-(4-(5,6-DIHYDRO-4H-1,2,4-OXADIAZIN-3-YL)PHENYL)-2-OXOOXAZOLIDIN-5-YL)METHYL)THIOPHENE-2-CARBOXAMIDE DERIVATIVES F2, F11, F5 KDM4E 112/4885ALDH1A1 1161/4885HPGD 565/4885
US-12503452-B2 Antimicrobial compounds and methods MPO, NISCH, RPN2 KDM4E 3027/4885ALDH1A1 3752/4885HPGD 1474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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