SCHEMBL25217371

SCHEMBL25217371

O=C1NC(=O)c2c(C[C@H]3CCO3)cccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.44
▸ KDM4E B2RXH2 5/20 0.44
▸ HPGD P15428 3/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ MAPK10 P53779 1/20 0.44
▸ CASP3 P42574 3/20 0.37
▸ GAA P10253 1/20 0.36
▸ GSK3B P49841 3/20 0.36
▸ PKM P14618 1/20 0.36
▸ PRKCB P05771 4/20 0.36
▸ PRKCG P05129 3/20 0.36
▸ PRKCA P17252 3/20 0.36
▸ PRKCH P24723 3/20 0.36
▸ PRKCZ Q05513 3/20 0.36
▸ PRKCD Q05655 3/20 0.36
▸ PARP1 P09874 2/20 0.36
▸ SRC P12931 2/20 0.36
▸ CYP1A2 P05177 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25256112 1.00 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL25256110 1.00 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL30352814 1.00 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL4716290 0.89 KDM4E (0.41) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL30614595 0.88 KDM4E (0.40) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL476301 0.88 KDM4E (0.40) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL3882337 0.88 KDM4E (0.40) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL932859 0.88 KDM4E (0.40) ALDH1A1KDM4EHPGDHSD17B10MAPK10
Methane SCHEMBL28294512 0.87 KDM4E (0.40) ALDH1A1KDM4EHPGDHSD17B10MAPK10
SCHEMBL28871836 0.81 GSK3B (0.41) ALDH1A1KDM4EHPGDHSD17B10MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540126-B2 Method for preparing oxetan-2-ylmethanamine ACCELA CHEMBIO CO., LTD. (CN) 2026-02-03 — — US disclosed
CN-115991685-B Preparation method of oxetane-2-methylamine 韶远科技(上海)有限公司 2025-03-04 — — CN disclosed
US-20240317695-A1 METHOD FOR PREPARING OXETAN-2-YLMETHANAMINE ACCELA CHEMBIO CO., LTD. (CN) 2024-09-26 — — US disclosed
EP-4194446-A1 PREPARATION METHOD FOR OXETANE-2-METHYLAMINE ACCELA CHEMBIO CO., LTD. (CN) 2023-06-14 — — EP disclosed
WO-2023065434-A1 PREPARATION METHOD FOR OXETANE-2-METHYLAMINE 韶远科技(上海)有限公司 2023-04-27 — — WO disclosed
CN-115991685-A Preparation method of oxetane-2-methylamine 韶远科技(上海)有限公司 2023-04-21 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540126-B2 Method for preparing oxetan-2-ylmethanamine TH, ALKBH2, ALKBH3 ALDH1A1 1775/4885KDM4E 207/4885HPGD 2281/4885
US-20240317695-A1 METHOD FOR PREPARING OXETAN-2-YLMETHANAMINE TH, TET1, TMT1A ALDH1A1 1838/4885KDM4E 131/4885HPGD 1771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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