SCHEMBL388268

SCHEMBL388268

Cc1ccc([PH](=O)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.48
LMNA P02545 2/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
HPGD P15428 2/20 0.41
TDP1 Q9NUW8 2/20 0.40
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
BCHE P06276 1/20 0.37
SMN1; SMN2 Q16637 5/20 0.37
ALDH1A1 P00352 1/20 0.37
CA12 O43570 2/20 0.36
CA9 Q16790 2/20 0.36
AKR1C3 P42330 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL27845318 0.92 ACHE (0.58) ACHELMNATSHRALOX12CES2
SCHEMBL183975 0.89 ACHE (0.50) ACHELMNATSHRALOX12CES2
SCHEMBL821938 0.87 ALDH1A1 (0.33) ACHELMNATSHRALOX12CES2
SCHEMBL1377101 0.85 ACHE (0.41) ACHELMNATSHRALOX12CES2
SCHEMBL1667 0.84 ALDH1A1 (0.35) ACHELMNATSHRALOX12CES2
SCHEMBL13583073 0.84 ALDH1A1 (0.35) ACHELMNATSHRALOX12CES2
Methyl Alcohol SCHEMBL28358130 0.81 CA2 (0.38) ACHELMNATSHRALOX12CES2
SCHEMBL20338478 0.81 ALDH1A1 (0.33) ACHELMNATSHRALOX12CES2
SCHEMBL28598523 0.81 ALDH1A1 (0.33) ACHELMNATSHRALOX12CES2
SCHEMBL30171495 0.81 ALDH1A1 (0.33) ACHELMNATSHRALOX12CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118006025-A Marine photovoltaic cable insulation sheath material and preparation method thereof 玖开特种线缆(上海)有限公司 2024-05-10 CN claimed
CN-115181286-A Guanidinophosphate hydrogen bond organic framework material and preparation method and application thereof 陕西科技大学 2022-10-14 CN claimed
CN-111574564-A Fluoroalkyl-substituted furyl diphosphine oxygen compound and preparation method thereof 南京工业大学 2020-08-25 CN claimed
CN-111560038-A Fluoroalkyl-substituted furyl monophosphine oxide compound and preparation method thereof 南京工业大学 2020-08-21 CN claimed
EP-0157315-B1 OPTICALLY ACTIVE DI(3-CHLOR-2-OXYPROPYL-TRIMETHYL-AMMONIUM) TARTRATE LONZA AG (CH) 1988-06-01 EP claimed
EP-0157315-A2 Optically active di(3-chlor-2-oxypropyl-trimethyl-ammonium) tartrate LONZA AG (CH) 1985-10-09 EP claimed
EP-4388030-A1 HIGH MOLECULAR WEIGHT POLYESTERAMIDES Solutia Inc. (US) 2024-06-26 EP disclosed
CN-118006025-B Marine photovoltaic cable insulation sheath material and preparation method thereof 玖开特种线缆(上海)有限公司 2024-06-18 CN disclosed
US-20240174857-A1 POLYESTERAMIDES, PROCESSES FOR THE PREPARATION THEREOF, AND POLYESTERAMIDE COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2024-05-30 US disclosed
CN-118006025-A Marine photovoltaic cable insulation sheath material and preparation method thereof 玖开特种线缆(上海)有限公司 2024-05-10 CN disclosed
CN-118006025-A Marine photovoltaic cable insulation sheath material and preparation method thereof 玖开特种线缆(上海)有限公司 2024-05-10 CN disclosed
US-20240117110-A1 POLYESTER COMPOSITIONS COMPRISING TETRAMETHYL-CYCLOBUTANEDIOL HAVING AN IMPROCED CATALYST SYSTEM COMPRISING LITHIUM AND GALLIUM ATOMS EASTMAN CHEMICAL COMPANY (US) 2024-04-11 US disclosed
US-20240117106-A1 POLYESTER COMPOSITIONS COMPRISING TETRAMETHYL CYCLOBUTANEDIOL AND 1,4-CYCLOHEXANEDIMETHANOL HAVING AN IMPROVED CATALYST SYSTEM COMPRISING TITANIUM AND ZINC EASTMAN CHEMICAL COMPANY (US) 2024-04-11 US disclosed
EP-0110089-B1 POLYMER-BOUND ALKYL DIARYLPHOSPHINITE CATALYST COMPOSITIONS AND PROCESSES FOR MAKING SAME AND USING SAME FOR SELECTIVE CONVERSION OF ACRYLONITRILE INTO 1,4-DICYANO-1-BUTENE ALLIED CORPORATION (US) 1988-01-07 EP disclosed
US-4710545-A REACTING CROSSLINKED DIVINYLBENZENE-STYRENE COPOLYMER WITH A PHOSPHORUS HALIDE, AROMATIC COMPOUND, WATER AND AN ALCOHOL ALLIED CORPORATION (US) 1987-12-01 US disclosed
US-4661615-A DIMERIZATION ALLIED CORPORATION (US) 1987-04-28 US disclosed
US-4581415-A DIMERIZATION OF ACRYLONITRILE; CATALYST SELECTIVITY; DURABILITY ALLIED CORPORATION (US) 1986-04-08 US disclosed
US-4574060-A Selective conversion of acrylonitrile into 1,4-dicyano-1-butene catalyzed by polymer-bound alkyl diarylphosphinites ALLIED CORPORATION (US) 1986-03-04 US disclosed
EP-0157315-A2 Optically active di(3-chlor-2-oxypropyl-trimethyl-ammonium) tartrate LONZA AG (CH) 1985-10-09 EP disclosed
EP-0110089-A2 Polymer-bound alkyl diarylphosphinite catalyst compositions and processes for making same and using same for selective conversion of acrylonitrile into 1,4-dicyano-1-butene ALLIED CORPORATION (US) 1984-06-13 EP disclosed