Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057322 | 0.78 | HTR2A (0.42) | TP53CYP2D6HSD17B10NPC1MTOR | |
| SCHEMBL13686299 | 0.75 | MAOB (0.48) | CYP2D6CYP2C9MAPK1CHRNA7LMNA | |
| SCHEMBL8382100 | 0.74 | TP53 (0.39) | TP53CYP2D6HSD17B10NPC1MTOR | |
| SCHEMBL4905648 | 0.74 | TP53 (0.39) | TP53CYP2D6HSD17B10NPC1MTOR | |
| SCHEMBL2098848 | 0.72 | RELA (0.46) | TP53CYP2D6HSD17B10MTORCYP3A4 | |
| SCHEMBL21596550 | 0.71 | LMNA (0.38) | TP53CYP2D6HSD17B10NPC1MTOR | |
| SCHEMBL21596552 | 0.71 | LMNA (0.38) | TP53CYP2D6HSD17B10NPC1MTOR | |
| SCHEMBL13686297 | 0.71 | ALDH1A1 (0.39) | MAPK1CHRNA7LMNACHRNB4CHRNA3 | |
| SCHEMBL8093709 | 0.71 | MEN1 (0.50) | TP53CYP2D6HSD17B10NPC1CYP3A4 | |
| SCHEMBL3882955 | 0.70 | CHRNA7 (0.43) | TP53CYP2D6HSD17B10NPC1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862384-A2 | POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | SiO2 Medical Products, Inc. (US) | 2021-08-11 | — | — | EP | disclosed |
| EP-1245636-B1 | COMPOSITION FOR HYDROGEL, HYDROGEL, AND USE THEREOF | NOF CORP (JP) | 2009-01-14 | — | — | EP | disclosed |