Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135426 | 0.91 | GRIN2B (0.35) | ALDH1A1S1PR1S1PR5GAAMAPT | |
| SCHEMBL2157193 | 0.74 | SMN1; SMN2 (0.33) | ALDH1A1MAPTPOLBMEN1HPGD | |
| SCHEMBL28625433 | 0.70 | HPGD (0.33) | ALDH1A1GAAPOLBHPGDL3MBTL1 | |
| SCHEMBL31559989 | 0.70 | APP (0.34) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL10245182 | 0.69 | TAAR1 (0.33) | EGFRGAAPOLBMAPK1L3MBTL1 | |
| SCHEMBL27902585 | 0.69 | MMP2 (0.35) | ALDH1A1POLBHTT | |
| SCHEMBL27630130 | 0.69 | PTPN1 (0.33) | FFAR1 | |
| SCHEMBL21043747 | 0.69 | PSEN1 (0.33) | ALDH1A1USP2HPGDMAPK1HSD17B10 | |
| SCHEMBL4181879 | 0.68 | MMP2 (0.37) | ALDH1A1HTT | |
| SCHEMBL5718581 | 0.68 | MAPT (0.30) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430025-B1 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING BACTERIAL INFECTION | ZHU DEXU (CN) | 2009-01-14 | — | — | EP | disclosed |