Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902585 | 0.96 | MMP2 (0.35) | CES2CES1SOAT1POLBEPHX1 | |
| SCHEMBL10440677 | 0.95 | MMP2 (0.37) | CES2CES1SOAT1OPRM1OPRD1 | |
| SCHEMBL4183422 | 0.95 | MMP2 (0.37) | CES2CES1SOAT1OPRM1OPRD1 | |
| SCHEMBL4184929 | 0.95 | MMP2 (0.37) | CES2CES1SOAT1OPRM1OPRD1 | |
| SCHEMBL4181879 | 0.95 | MMP2 (0.37) | CES2CES1SOAT1OPRM1OPRD1 | |
| SCHEMBL9746020 | 0.95 | MMP2 (0.37) | CES2CES1SOAT1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL9852429 | 0.94 | MMP2 (0.36) | CES2CES1SOAT1OPRM1OPRD1 | |
| SCHEMBL7510602 | 0.92 | SMN1; SMN2 (0.33) | HPGDKDM4ESMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL27724005 | 0.91 | HPGD (0.32) | HPGDGAAHDAC3HDAC1HDAC2 | |
| SCHEMBL2157193 | 0.86 | SMN1; SMN2 (0.33) | HPGDKDM4ESMN1; SMN2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520413-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-108884058-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-109219596-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-106661084-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2021-08-31 | — | — | CN | disclosed |