Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510602 | 0.88 | SMN1; SMN2 (0.33) | SMN1; SMN2L3MBTL1MAPTCHRM2CHRM4 | |
| SCHEMBL28625433 | 0.86 | HPGD (0.33) | SMN1; SMN2L3MBTL1HPGDALDH1A1KDM4E | |
| SCHEMBL4459328 | 0.85 | SRR (0.32) | FFAR1 | |
| SCHEMBL27630130 | 0.85 | PTPN1 (0.33) | FFAR1 | |
| SCHEMBL27902585 | 0.85 | MMP2 (0.35) | ALDH1A1POLB | |
| SCHEMBL21043747 | 0.84 | PSEN1 (0.33) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4184929 | 0.84 | MMP2 (0.37) | ALDH1A1 | |
| SCHEMBL5718581 | 0.84 | MAPT (0.30) | MAPT | |
| SCHEMBL9746020 | 0.84 | MMP2 (0.37) | ALDH1A1 | |
| SCHEMBL4183422 | 0.84 | MMP2 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1515541-A | Method for detecting ligand pair combination by using non-fluorescent marker and its composite | ռ�˹ | 2004-07-28 | — | — | CN | claimed |
| WO-2000022909-A2 | SYSTEMS FOR ORAL DELIVERY | BIOTECH AUSTRALIA PTY. LIMITED (AU) | 2000-04-27 | — | — | WO | claimed |
| CN-1212019-A | Methods and compositions for detecting ligand pair binding using non-fluorescent labels | RAPIGENE INC (US) | 1999-03-24 | — | — | CN | claimed |
| CN-117981493-A | Light-emitting element, method for manufacturing light-emitting element, display device, and method for manufacturing display device | 夏普显示科技株式会社 | 2024-05-03 | — | — | CN | disclosed |
| CN-101550077-B | Manufacturing method of bicyclohexyl derivative | FUJI PHOTO FILM CO LTD | 2013-09-25 | — | — | CN | disclosed |
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |
| CN-101765585-A | Antibacterial agent | ACHAOGEN INC | 2010-06-30 | — | — | CN | disclosed |
| EP-1404372-B1 | PHARMACEUTICAL FORMULATIONS AND LIGANDS FOR USE THEREIN; MIMETICS FOR UEA-1 | SARLAN LTD (BM) | 2010-03-03 | — | — | EP | disclosed |
| CN-101550077-A | Manufacturing method of bicyclohexyl derivative | FUJI PHOTO FILM CO LTD (JP) | 2009-10-07 | — | — | CN | disclosed |
| US-20090043099-A1 | Methods and compositions for derepression of IAP-inhibited caspase | THE BURNHAM INSTITUTE (US) | 2009-02-12 | — | — | US | disclosed |
| EP-1951278-A2 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | The Burnham Institute (US) | 2008-08-06 | — | — | EP | disclosed |
| US-6545032-B1 | Combinatorial libraries | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2003-04-08 | — | — | US | disclosed |
| EP-1218337-A4 | SYNTHESIS OF 3,5,7]-1H-IMIDAZO 1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INST (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1218337-A1 | SYNTHESIS OF 3,5,7]-1H-IMIDAZO 1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2002-07-03 | — | — | EP | disclosed |
| US-6359144-B1 | BIOSYNTHESIS; SCREENING | LION BIOSCIENCE AG (DE) | 2002-03-19 | — | — | US | disclosed |
| WO-2001019783-A1 | SYNTHESIS OF [3,5,7]-1H-IMIDAZO[1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2001-03-22 | — | — | WO | disclosed |
| WO-2000022909-A2 | SYSTEMS FOR ORAL DELIVERY | BIOTECH AUSTRALIA PTY. LIMITED (AU) | 2000-04-27 | — | — | WO | disclosed |
| CN-1212019-A | Methods and compositions for detecting ligand pair binding using non-fluorescent labels | RAPIGENE INC (US) | 1999-03-24 | — | — | CN | disclosed |
| US-5856107-A | Combinatorial libraries of imidazol-pyrido-indole and imidazol-pyrido-benzothiophene derivatives, methods of making the libraries and compounds therein | TREGA BIOSCIENCES, INC. (US) | 1999-01-05 | — | — | US | disclosed |
| WO-1998034112-A1 | COMBINATORIAL LIBRARIES OF IMIDAZOL-PYRIDO-INDOLES AND IMIDAZOL-PYRIDO-BENZOTHIOPHENE DERIVATIVES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043099-A1 | Methods and compositions for derepression of IAP-inhibited caspase | BIRC5, API5, BIRC3 | SMN1; SMN2 2861/4885L3MBTL1 566/4885MAPT 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.