Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 4/20 | 0.37 |
| ▸ | YES1 | P07947 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894528 | 0.91 | BRD4 (0.46) | BRD4PTGDR2SRC | |
| SCHEMBL3882579 | 0.90 | IKBKB (0.40) | RORCBRD4PTGDR2SRCYES1 | |
| SCHEMBL3883511 | 0.88 | BRD4 (0.39) | RORCBRD4ALDH1A1PTGDR2SRC | |
| SCHEMBL3895970 | 0.88 | SCN9A (0.39) | RORCSRCYES1KEAP1NFE2L2 | |
| SCHEMBL3883607 | 0.86 | FFAR4 (0.43) | RORCBRD4ALDH1A1L3MBTL1PTGDR2 | |
| SCHEMBL3882520 | 0.86 | KEAP1 (0.38) | SRCYES1KEAP1NFE2L2PTGER1 | |
| SCHEMBL3882409 | 0.86 | PTGER1 (0.42) | SRCYES1KEAP1NFE2L2PTGER1 | |
| SCHEMBL3890246 | 0.85 | PTGER1 (0.40) | SRCYES1KEAP1NFE2L2PTGER1 | |
| SCHEMBL3882287 | 0.85 | BRD4 (0.41) | BRD4SRCYES1KEAP1NFE2L2 | |
| SCHEMBL3884439 | 0.84 | C5AR1 (0.42) | SRCYES1KEAP1NFE2L2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |