Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17743752 | 0.89 | FFAR1 (0.52) | SMN1; SMN2HDAC6FFAR1KMT2AMEN1 | |
| Adipic Acid SCHEMBL3282524 | 0.83 | FFAR1 (0.49) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL3884465 | 0.81 | CYP4F2 (0.48) | SMN1; SMN2HSD17B10KMT2AMEN1CYP1A2 | |
| SCHEMBL27965286 | 0.80 | P2RX7 (0.44) | SMN1; SMN2FFAR1KMT2AMEN1OPRM1 | |
| SCHEMBL19837458 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2FFAR1KMT2AMEN1OPRM1 | |
| SCHEMBL7437586 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL7437968 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL15820943 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL4314841 | 0.78 | KCNH2 (0.47) | SMN1; SMN2KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL869497 | 0.78 | KMT2A (0.53) | SMN1; SMN2FFAR1KMT2AMEN1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882712-B1 | PROCESS FOR PREPARING ACID SALTS OF GAMMA-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6197961-B1 | HYDROGENATION OF G-(PYRIDYL)BUTYRIC ACID SALT IN SOLVENT USING PALLADIUM, RHODIUM, OR RUTHENIUM CATALYST; HYDROLYSIS, DECARBOXYLATION | KOEI CHEMICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0882712-A1 | PROCESS FOR PREPARING ACID SALTS OF $g(g)-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |