Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.68 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882407 | 0.86 | GPR17 (0.64) | GPR17CYP19A1L3MBTL1LMNAMAPT | |
| SCHEMBL3883213 | 0.84 | CYP19A1 (0.57) | GPR17GPR55CYP19A1CA12CYP1A2 | |
| SCHEMBL3875842 | 0.82 | HTT (0.75) | GPR55LMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL27450611 | 0.81 | CYP19A1 (0.74) | GPR17CYP19A1CA12CYP1A2CYP3A4 | |
| SCHEMBL3873636 | 0.81 | CYP19A1 (0.59) | GPR55CYP19A1CA12CYP1A2CYP3A4 | |
| SCHEMBL31224707 | 0.80 | MAPT (0.64) | GPR17GPR55CYP19A1LMNAMAPT | |
| SCHEMBL3874748 | 0.80 | NAMPT (0.60) | GPR55CYP19A1CA12CA9LMNA | |
| SCHEMBL3872637 | 0.79 | CYP19A1 (0.56) | GPR55CYP19A1CA12CYP1A2CYP3A4 | |
| SCHEMBL3873119 | 0.77 | HTT (0.67) | GPR55LMNAPOLBALDH1A1 | |
| SCHEMBL29019313 | 0.77 | CA12 (0.82) | GPR55CYP19A1CA12CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814846-B1 | 11BETA-HSD1 INHIBITORS | EVOTEC AG (DE) | 2009-04-08 | — | — | EP | disclosed |
| US-20090069323-A1 | 11beta-hsdi inhibitors | EVOTEC AG (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069323-A1 | 11beta-hsdi inhibitors | HSD3B1, HSD3B2, HSD11B1 | GPR17 3455/4885GPR55 2780/4885CYP19A1 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.