Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.53 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884841 | 0.86 | GPR17 (0.68) | GPR17CYP19A1MAPTPOLBRECQL | |
| SCHEMBL3873257 | 0.82 | ENPP2 (0.55) | MAPTENPP2POLBRAB9ANPC1 | |
| SCHEMBL3871576 | 0.80 | POLB (0.78) | CYP19A1MAPTPOLBRECQLMEN1 | |
| SCHEMBL3876577 | 0.78 | CYP19A1 (0.67) | CYP19A1MAPTPOLBRECQLMEN1 | |
| SCHEMBL3872817 | 0.77 | HTT (0.68) | CYP19A1POLBRAB9AF2F10 | |
| SCHEMBL28003778 | 0.77 | CYP19A1 (0.70) | CYP19A1MAPTPOLBRECQLMEN1 | |
| SCHEMBL3876662 | 0.76 | HSD11B1 (0.60) | CYP19A1POLBRAB9ANPC1KMT2A | |
| SCHEMBL27450611 | 0.76 | CYP19A1 (0.74) | GPR17CYP19A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL3879290 | 0.76 | ALDH1A1 (0.66) | CYP19A1POLBNPC1MEN1KMT2A | |
| SCHEMBL12447826 | 0.75 | NPC1 (0.82) | MAPTENPP2POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814846-B1 | 11BETA-HSD1 INHIBITORS | EVOTEC AG (DE) | 2009-04-08 | — | — | EP | disclosed |
| US-20090069323-A1 | 11beta-hsdi inhibitors | EVOTEC AG (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069323-A1 | 11beta-hsdi inhibitors | HSD3B1, HSD3B2, HSD11B1 | GPR17 3455/4885CYP19A1 23/4885MAPT 4169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.