Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008911 | 1.00 | THRA (0.47) | THRATHRBFFAR4FFAR1F7 | |
| SCHEMBL3893894 | 0.99 | THRA (0.45) | THRATHRBFFAR4FFAR1F7 | |
| SCHEMBL3893900 | 0.99 | THRA (0.45) | THRATHRBFFAR4FFAR1F7 | |
| SCHEMBL3881793 | 0.91 | THRA (0.36) | THRATHRBFFAR4ENPP2PTGS2 | |
| SCHEMBL3682491 | 0.90 | CHEK1 (0.37) | THRATHRBFFAR4ENPP2PTGS2 | |
| SCHEMBL3888474 | 0.88 | THRA (0.46) | THRATHRBFFAR4F7F3 | |
| SCHEMBL3888470 | 0.88 | THRA (0.46) | THRATHRBFFAR4F7F3 | |
| SCHEMBL3884991 | 0.88 | ENPP2 (0.38) | THRATHRBFFAR4F7F3 | |
| SCHEMBL3884996 | 0.88 | ENPP2 (0.38) | THRATHRBFFAR4F7F3 | |
| SCHEMBL3884845 | 0.86 | THRA (0.49) | THRATHRBFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |