Hydrochloric Acid

Hydrochloric Acid

SCHEMBL38849

C/C(=N\c1ccc(F)cc1F)c1cccc(/C(C)=N/c2ccc(F)cc2F)n1.[Cl-].[Cl-].[Fe+2]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.35
AGTR1 P30556 2/20 0.35
RAB9A P51151 2/20 0.35
ALDH1A1 P00352 5/20 0.34
MAPT P10636 4/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
POLB P06746 1/20 0.34
ALOX12 P18054 1/20 0.34
KDM4E B2RXH2 2/20 0.33
HTR1F P30939 1/20 0.33
GAA P10253 1/20 0.33
LMNA P02545 1/20 0.33
MPI P34949 1/20 0.33
HTT P42858 1/20 0.33
MT-CO1 P00395 1/20 0.32
MT-CO2 P00403 1/20 0.32
EDNRA P25101 1/20 0.32
OPRM1 P35372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14761757 1.00 NPC1 (0.35) NPC1AGTR1RAB9AALDH1A1MAPT
Hydrochloric Acid SCHEMBL2577967 1.00 NPC1 (0.35) NPC1AGTR1RAB9AALDH1A1MAPT
SCHEMBL23457659 0.97 ALDH1A1 (0.36) NPC1AGTR1RAB9AALDH1A1MAPT
SCHEMBL23457658 0.97 ALDH1A1 (0.36) NPC1AGTR1RAB9AALDH1A1MAPT
SCHEMBL28376119 0.95 ALDH1A1 (0.35) NPC1AGTR1RAB9AALDH1A1MAPT
SCHEMBL23457823 0.91 ALDH1A1 (0.34) NPC1AGTR1RAB9AALDH1A1MAPT
Hydrochloric Acid SCHEMBL11898801 0.84 OPRK1 (0.31) NPC1AGTR1MAPTKMT2ATDP1
Hydrochloric Acid SCHEMBL819734 0.84 OPRK1 (0.31) NPC1AGTR1MAPTKMT2ATDP1
Hydrochloric Acid SCHEMBL3295940 0.83 NPC1 (0.40) NPC1AGTR1RAB9AALDH1A1MAPT
Hydrochloric Acid SCHEMBL3295936 0.83 NPC1 (0.40) NPC1AGTR1RAB9AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11999839-B2 Polyethylene composition for filaments or fibers BASELL POLYOLEFINE GMBH (DE) 2024-06-04 US disclosed
EP-4069775-B1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2024-04-03 EP disclosed
EP-4069774-B1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2024-01-17 EP disclosed
US-20230075830-A1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2023-03-09 US disclosed
US-20230002598-A1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2023-01-05 US disclosed
EP-2935414-B2 POLYETHYLENE COMPOSITION HAVING HIGH MECHANICAL PROPERTIES BASELL POLYOLEFINE GMBH (DE) 2021-11-17 EP disclosed
WO-2021110769-A1 POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS BASELL POLYOLEFINE GMBH (DE) 2021-06-10 WO disclosed
EP-3058025-B2 POLYETHYLENE INJECTION MOULDING ARTICLES BASELL POLYOLEFINE GMBH (DE) 2020-04-22 EP disclosed
EP-3058026-B2 POLYETHYLENE FOR INJECTION MOULDING BASELL POLYOLEFINE GMBH (DE) 2020-04-15 EP disclosed
EP-3058002-B1 POLYETHYLENE OF RAISED TEMPERATURE RESISTANCE BASELL POLYOLEFINE GMBH (DE) 2019-08-21 EP disclosed
EP-2935414-A1 POLYETHYLENE COMPOSITION HAVING HIGH MECHANICAL PROPERTIES Basell Polyolefine GmbH (DE) 2015-10-28 EP disclosed
WO-2015055394-A1 POLYETHYLENE COMPOSITION FOR INJECTION MOULDING BASELL POLYOLEFINE GMBH (DE) 2015-04-23 WO disclosed
WO-2015055392-A1 POLYETHYLENE OF RAISED TEMPERATURE RESISTANCE BASELL POLYOLEFINE GMBH (DE) 2015-04-23 WO disclosed
WO-2015055393-A1 POLYETHYLENE FOR INJECTION MOULDING BASELL POLYOLEFINE GMBH (DE) 2015-04-23 WO disclosed
WO-2014095231-A1 POLYETHYLENE COMPOSITION HAVING HIGH MECHANICAL PROPERTIES BASELL POLYOLEFINE GMBH (DE) 2014-06-26 WO disclosed
EP-2746320-A1 Polyethylene composition having high mechanical properties Basell Polyolefine GmbH (DE) 2014-06-25 EP disclosed
US-8716423-B2 Polyethylene for rotomoulding BASELL POLYOLEFINE GMBH (DE) 2014-05-06 US disclosed
US-20130064995-A1 Polymer Filament or Fiber BASELL POLYOLEFINE GMBH (DE) 2013-03-14 US disclosed
EP-2563957-A2 POLYMER FILAMENT OR FIBER Basell Polyolefine GmbH (DE) 2013-03-06 EP disclosed
WO-2011134897-A2 POLYMER FILAMENT OR FIBER BASELL POLYOLEFINE GMBH (DE) 2011-11-03 WO disclosed