⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268174 | 1.00 | — | — | |
| SCHEMBL464808 | 1.00 | — | — | |
| SCHEMBL28080548 | 0.93 | NOS2 (0.39) | — | |
| SCHEMBL2494402 | 0.84 | NOS2 (0.43) | — | |
| SCHEMBL6859669 | 0.84 | NOS2 (0.46) | — | |
| SCHEMBL995604 | 0.84 | NOS2 (0.46) | — | |
| SCHEMBL146828 | 0.84 | NOS2 (0.46) | — | |
| SCHEMBL2637808 | 0.83 | NOS2 (0.42) | — | |
| Proline SCHEMBL8941802 | 0.82 | BLM (0.47) | — | |
| SCHEMBL4336849 | 0.81 | EPHX1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711533-B1 | Methods of producing peptides/proteins in plants and peptides/proteins produced thereby | UNIV OHIO (US) | 2013-12-11 | — | — | EP | claimed |
| EP-2133427-B1 | Methods of producing peptides/proteins in plants and peptides/proteins produced thereby | UNIV OHIO (US) | 2013-12-11 | — | — | EP | claimed |
| US-20110230404-A1 | Glycoproteins Produced in Plants and Methods of Their Use | OHIO UNIVERSITY (US) | 2011-09-22 | — | — | US | claimed |
| US-20100029548-A1 | GLYCOPROTEINS PRODUCED IN PLANTS AND METHODS OF THEIR USE | OHIO UNIVERSITY (US) | 2010-02-04 | — | — | US | claimed |
| EP-2133427-A1 | Methods of producing peptides/proteins in plants and peptides/proteins produced thereby | Ohio University (US) | 2009-12-16 | — | — | EP | claimed |
| US-20250026819-A1 | METHODS OF TREATMENT COMPRISING ANTIBODIES BINDING TO ALPHA7BETA1 INTEGRIN ANTIBODIES | PLIANT THERAPEUTICS, INC. | 2025-01-23 | — | — | US | disclosed |
| US-12134642-B2 | Antibodies binding to α7β1 integrin antibodies and compositions thereof | PLIANT THERAPEUTICS, INC. (US) | 2024-11-05 | — | — | US | disclosed |
| US-11904004-B2 | Anti-CD277 antibodies | INSERM (FR) | 2024-02-20 | — | — | US | disclosed |
| US-20240043541-A1 | METHODS FOR TREATING HEMATOLOGIC CANCERS | NOVARTIS AG (CH) | 2024-02-08 | — | — | US | disclosed |
| US-11873486-B2 | Modulating dsRNA editing, sensing, and metabolism to increase tumor immunity and improve the efficacy of cancer immunotherapy and/or modulators of intratumoral interferon | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-20240010749-A1 | ANTI-CEACAM5 ANTIBODIES AND CONJUGATES AND USES THEREOF | MERCK PATENT GMBH (DE) | 2024-01-11 | — | — | US | disclosed |
| US-20230416399-A1 | METHODS FOR TREATING CANCER WITH ANTI-GD2/GD3 ANTIBODIES | SARAGOVI HORACIO URI (CA) | 2023-12-28 | — | — | US | disclosed |
| US-7378506-B2 | Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins | OHIO UNIVERSITY (US) | 2008-05-27 | — | — | US | disclosed |
| WO-2008053330-A2 | MONOCLONAL ANTIBODIES AGAINST THE HUMAN ANTI-MULLERIAN HORMONE TYPE II RECEPTOR (AMHR-II) | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-05-08 | — | — | WO | disclosed |
| EP-1918304-A1 | Monoclonal antibodies against the human anti-müllerian hormone type II receptor (AMHR-II) | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2008-05-07 | — | — | EP | disclosed |
| EP-1622635-A4 | SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE-RICH GLYCOPROTEINS | UNIV OHIO (US) | 2008-01-23 | — | — | EP | disclosed |
| EP-1622635-A2 | SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE-RICH GLYCOPROTEINS | Ohio University (US) | 2006-02-08 | — | — | EP | disclosed |
| US-20050074838-A1 | Recombinant polypeptides comprising proline rich regions for use as tool in slow release drug delivery | OHIO UNIVERSITY, TECHNOLOGY TRANSFER OFFICE, TECHNOLOGY | 2005-04-07 | — | — | US | disclosed |
| WO-2004094590-A2 | SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE-RICH GLYCOPROTEINS | OHIO UNIVERSITY (US) | 2004-11-04 | — | — | WO | disclosed |
| WO-2004034984-A2 | CELL-SEEDED TISSUE-ENGINEERED POLYMERS FOR TREATMENT OF INTRACRANIAL ANEURYSMS | THE GENERAL HOSPITAL CORPORATION (US) | 2004-04-29 | — | — | WO | disclosed |