SCHEMBL995604

SCHEMBL995604

O=C(OC(=O)[C@@H]1CCCN1)[C@@H]1CCCN1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.46
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
DPP4 P27487 6/20 0.43
DPP8 Q6V1X1 4/20 0.42
DPP9 Q86TI2 4/20 0.42
FAP Q12884 1/20 0.41
DPP7 Q9UHL4 1/20 0.41
ELANE P08246 1/20 0.40
PRCP P42785 1/20 0.40
GLI1 P08151 1/20 0.39
MEN1 O00255 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
SCN4A P35499 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL146828 1.00 NOS2 (0.46) NOS2NOS3NOS1DPP4DPP8
SCHEMBL6859669 1.00 NOS2 (0.46) NOS2NOS3NOS1DPP4DPP8
SCHEMBL9737609 0.96 NOS2 (0.43) NOS2NOS3NOS1DPP4DPP8
SCHEMBL31298402 0.94 NOS2 (0.42) NOS2NOS3NOS1DPP4DPP8
SCHEMBL10885146 0.93 NOS2 (0.40) NOS2NOS3NOS1DPP4DPP8
SCHEMBL17503226 0.89 NOS2 (0.42) NOS2NOS3NOS1DPP4DPP8
SCHEMBL28288006 0.89 NOS2 (0.42) NOS2NOS3NOS1DPP4DPP8
SCHEMBL10888007 0.87 NOS2 (0.40) NOS2NOS3NOS1DPP4PRCP
SCHEMBL2228248 0.87 NOS2 (0.41) NOS2NOS3NOS1DPP4DPP8
SCHEMBL4001212 0.87 NOS2 (0.41) NOS2NOS3NOS1DPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101333221-B Stabilization method for annular L-proline anhydride configuration UNIV WUHAN 2011-01-19 CN claimed
CN-101333221-A Stabilization method for annular L-proline anhydride configuration UNIV WUHAN (CN) 2008-12-31 CN claimed
CN-1243757-C Chelating chiral boric acid ester and preparatio process and use thereof UNIV WUHAN (CN) 2006-03-01 CN claimed
CN-1228296-C Preparation process of 100%ee (R)or (s) 1,1-2-binaphthol UNIV WUHAN (CN) 2005-11-23 CN claimed
CN-1560006-A Preparation process of 100%ee (R)or (s) 1,1-2-binaphthol 武汉大学 2005-01-05 CN claimed
CN-118146298-A Short peptide RQRG and application thereof in agriculture 北方民族大学 2024-06-07 CN disclosed
CN-116036076-A Application of lithium amino acid in preparation of medicine for treating manic mental diseases 安域生物科技(杭州)有限公司 2023-05-02 CN disclosed
CN-115813913-A Application of proline or isobutyric acid in preparation of auxiliary drugs of central nervous excitation drugs 安域生物科技(杭州)有限公司 2023-03-21 CN disclosed
US-20210054397-A1 YIELD AND STRESS TOLERANCE IN TRANSGENIC PLANTS IV MENDEL BIOTECHNOLOGY INC (US) 2021-02-25 US disclosed
EP-3741853-A1 METHODS OF CELL SELECTION AND MODIFYING CELL METABOLISM Lonza Ltd. (CH) 2020-11-25 EP disclosed
US-10787677-B2 Yield and stress tolerance in transgenic plants IV MENDEL BIOTECHNOLOGY, INC. (US) 2020-09-29 US disclosed
US-10597667-B2 Stress tolerance in plants MENDEL BIOTECHNOLOGY, INC. (US) 2020-03-24 US disclosed
US-5273885-A Using a polyiodothyronine analog of a phenyl compound containing a hydroxyl group ortho to an iodine SYNTEX (U.S.A.) INC. (US) 1993-12-28 US disclosed
US-4376825-A ENZYME-BOUND LIGANDS WITH FREE REACTIVE SITES WHICH CAN BIND RECEPTORS SYVA COMPANY (US) 1983-03-15 US disclosed
US-4282325-A FOR AMPLIFICATION IN ASSAYS SYVA COMPANY (US) 1981-08-04 US disclosed
US-4203802-A ENZYME BOUND TO AN ESTROGEN LIGAND SYVA COMPANY (US) 1980-05-20 US disclosed
US-4190496-A RECEPTOR, LIGAND, AND ENZYME-BOUND SYVA COMPANY (US) 1980-02-26 US disclosed
US-4067774-A Compounds for enzyme amplification assay SYVA COMPANY (US) 1978-01-10 US disclosed
US-3975237-A LIGANDS SYVA COMPANY (US) 1976-08-17 US disclosed
US-3966556-A Compounds for enzyme amplification assay methadone analogs SYVA COMPANY (US) 1976-06-29 US disclosed