Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 6/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | GLI1 | P08151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146828 | 1.00 | NOS2 (0.46) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL995604 | 1.00 | NOS2 (0.46) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL9737609 | 0.96 | NOS2 (0.43) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL31298402 | 0.94 | NOS2 (0.42) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL10885146 | 0.93 | NOS2 (0.40) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL17503226 | 0.89 | NOS2 (0.42) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL28288006 | 0.89 | NOS2 (0.42) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL10888007 | 0.87 | NOS2 (0.40) | NOS2NOS3NOS1DPP4PRCP | |
| SCHEMBL2228248 | 0.87 | NOS2 (0.41) | NOS2NOS3NOS1DPP4DPP8 | |
| SCHEMBL4001212 | 0.87 | NOS2 (0.41) | NOS2NOS3NOS1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129116-A2 | A DRUG FOR THE TREATMENT OF TYPE 2 DIABETES MELLITUS DISEASE AND THE NANOPARTICLE THEREOF | GAZIANTEP UNIVERSITESI REKTORLUGU (TR) | 2023-07-06 | — | — | WO | disclosed |
| US-6835808-B2 | Synthetic oligopeptide heparin-neutralizing agents including basic amino acids and a N-heterocyclic end group; low turbidity; side effects reduction; in vitro diagnosis; calculate the blood clotting time; assaying clotting cascade | DIAGNOSTICA-STAGO (FR) | 2004-12-28 | — | — | US | disclosed |