Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 3/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891467 | 0.98 | DNM1 (0.49) | DNM1NAAAKDM5ADGKAS1PR2 | |
| SCHEMBL254321 | 0.98 | DNM1 (0.44) | DNM1NAAAKDM5ADGKAS1PR2 | |
| SCHEMBL31494293 | 0.85 | ALDH1A1 (0.39) | DNM1NAAAALDH1A1KDM5C | |
| SCHEMBL11412630 | 0.84 | DNM1 (0.56) | DNM1KDM5ADGKAALDH1A1CES2 | |
| SCHEMBL2750539 | 0.83 | DNM1 (0.42) | DNM1KDM5AS1PR2S1PR1S1PR3 | |
| SCHEMBL8781867 | 0.81 | ALDH1A1 (0.41) | DNM1KDM5AS1PR2S1PR1S1PR3 | |
| SCHEMBL31190462 | 0.80 | DNM1 (0.60) | DNM1DGKACES2CES1LMNA | |
| SCHEMBL25198827 | 0.79 | NAAA (0.50) | DNM1NAAAKDM5ADGKAALDH1A1 | |
| SCHEMBL25211926 | 0.79 | NAAA (0.50) | DNM1NAAAKDM5ADGKAALDH1A1 | |
| SCHEMBL25218755 | 0.79 | NAAA (0.50) | DNM1NAAAKDM5ADGKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010549-A1 | CRYSTALLINE FORMS OF IBANDRONIC ACID AND PROCESSES FOR PREPARATION THEREOF | Teva Pharmaceutical Industries Ltd (IL) | 2009-01-07 | — | — | EP | claimed |
| WO-2007127249-A1 | CRYSTALLINE FORMS OF IBANDRONIC ACID AND PROCESSES FOR PREPARATION THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-11-08 | — | — | WO | claimed |