Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238755 | 0.98 | — | — | |
| SCHEMBL1427314 | 0.86 | CYP2B6 (0.35) | CYP2B6 | |
| SCHEMBL3232963 | 0.86 | CYP2B6 (0.35) | CYP2B6 | |
| SCHEMBL3007493 | 0.84 | CTSL (0.35) | CYP2B6 | |
| SCHEMBL16026414 | 0.73 | — | — | |
| SCHEMBL3237591 | 0.71 | — | — | |
| SCHEMBL1035871 | 0.67 | CYP2B6 (0.35) | CYP2B6 | |
| SCHEMBL2285285 | 0.67 | CYP2B6 (0.35) | CYP2B6 | |
| SCHEMBL15721208 | 0.65 | RAB9A (0.33) | — | |
| SCHEMBL6783509 | 0.64 | HRH3 (0.34) | CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227629-A1 | COMPOUNDS HAVING ACTIVITY AT THE GLYCINE TRANSPORTER GLYT1 AND USES THEREOF | GLAXO GROUP LIMITED | 2009-09-10 | — | — | US | disclosed |
| EP-2013173-A2 | PYRIDINE-, ISOXAZOLE, THIOPHENECARBOXAMIDE COMPOUNDS HAVING ACTIVITY AT THE GLYCINE TRANSPORTER GLYT1 AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007080159-A2 | PYRIDINE-, ISOXAZOLE, THIOPHENECARBOXAMIDE COMPOUNDS HAVING ACTIVITY AT THE GLYCINE TRANSPORTER GLYT1 AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227629-A1 | COMPOUNDS HAVING ACTIVITY AT THE GLYCINE TRANSPORTER GLYT1 AND USES THEREOF | SLC18A2, SLC6A3, SLC6A2 | CYP2B6 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.