SCHEMBL3886443

SCHEMBL3886443

CC[Si](O)(O)C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.33
ADH1A P07327 2/20 0.32
ADH1C P00326 1/20 0.32
CYP1A2 P05177 1/20 0.32
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955128 0.79 CYP1A2 (0.37) SHBGADH1AADH1CCYP1A2CA1
SCHEMBL8955463 0.79 CYP1A2 (0.37) SHBGADH1AADH1CCYP1A2CA1
SCHEMBL3898081 0.79 CYP1A2 (0.37) SHBGADH1AADH1CCYP1A2CA1
SCHEMBL8955288 0.76 CYP1A2 (0.33) CYP1A2CA1CA2CA4
SCHEMBL2021845 0.76 CA1 (0.31) CA1CA2CA4
SCHEMBL8955104 0.75 CYP1A2 (0.39) SHBGCYP1A2KDM4ECA1CA2
SCHEMBL8955562 0.75 CYP1A2 (0.39) SHBGCYP1A2KDM4ECA1CA2
SCHEMBL8956015 0.75 CYP1A2 (0.39) SHBGCYP1A2KDM4ECA1CA2
SCHEMBL4536242 0.75 GNAI3 (0.31)
SCHEMBL3889883 0.72 SHBG (0.36) SHBGADH1AADH1CCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9884879-B2 Method of synthesizing siloxane monomers and use thereof SILECS OY (FI) 2018-02-06 US claimed
US-20170088565-A1 Method of synthesizing siloxane monomers and use thereof SILECS OY (FI) 2017-03-30 US claimed
US-20140249326-A1 Method of Synthesizing Siloxane Monomers and Use Thereof SILECS OY (FI) 2014-09-04 US claimed
WO-2012172176-A9 METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF SILECS OY (FI) 2013-02-07 WO claimed
WO-2012172176-A2 METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF SILECS OY (FI) 2012-12-20 WO claimed
US-9884879-B2 Method of synthesizing siloxane monomers and use thereof SILECS OY (FI) 2018-02-06 US disclosed
US-20170088565-A1 Method of synthesizing siloxane monomers and use thereof SILECS OY (FI) 2017-03-30 US disclosed
US-9458183-B2 Method of synthesizing siloxane monomers and use thereof SILECS OY (FI) 2016-10-04 US disclosed
US-20140249326-A1 Method of Synthesizing Siloxane Monomers and Use Thereof SILECS OY (FI) 2014-09-04 US disclosed
WO-2012172176-A9 METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF SILECS OY (FI) 2013-02-07 WO disclosed
WO-2012172176-A2 METHOD OF SYNTHESIZING SILOXANE MONOMERS AND USE THEREOF SILECS OY (FI) 2012-12-20 WO disclosed
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170088565-A1 Method of synthesizing siloxane monomers and use thereof MSMO1, PCNA, PIEZO1 SHBG 2635/4885ADH1A 1365/4885ADH1C 1315/4885
US-20140249326-A1 Method of Synthesizing Siloxane Monomers and Use Thereof MSMO1, PCNA, PIEZO1 SHBG 2635/4885ADH1A 1365/4885ADH1C 1315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.