Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885225 | 0.90 | PTGER1 (0.46) | S1PR1S1PR5PTGS2PTGER1PTGER4 | |
| SCHEMBL3891560 | 0.90 | PTGER1 (0.44) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3891017 | 0.87 | PTGS2 (0.43) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3882397 | 0.87 | PTGER1 (0.44) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3891583 | 0.87 | PTGER1 (0.46) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3882813 | 0.86 | MAOB (0.42) | S1PR1S1PR5PTGS2PTGER1PTGER4 | |
| SCHEMBL3882394 | 0.86 | PTGER1 (0.42) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3885383 | 0.85 | FFAR1 (0.48) | S1PR1S1PR5 | |
| SCHEMBL3886809 | 0.85 | PTGS2 (0.42) | PTGS2ENPP2PPARA | |
| SCHEMBL3890174 | 0.84 | PTGER1 (0.53) | PTGS2PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |