Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894657 | 0.92 | PPARA (0.46) | PTGS2PPARAPPARDP2RX3ENPP2 | |
| SCHEMBL3882075 | 0.92 | PTGS2 (0.43) | PTGS2PPARAPPARDENPP2MAP3K11 | |
| SCHEMBL3884148 | 0.91 | ENPP2 (0.39) | PTGS2PPARAPPARDENPP2PPARG | |
| SCHEMBL3891560 | 0.91 | PTGER1 (0.44) | PTGS2PPARAP2RX3ENPP2MAP3K11 | |
| SCHEMBL3883391 | 0.90 | PTGS2 (0.41) | PTGS2PPARAPPARDENPP2MAP3K11 | |
| SCHEMBL3884675 | 0.88 | PTGER1 (0.41) | PTGS2PPARAPPARDENPP2MAP3K11 | |
| SCHEMBL3894495 | 0.87 | PTGS2 (0.41) | PTGS2PPARAPPARDENPP2PPARG | |
| SCHEMBL3882300 | 0.87 | PTGS2 (0.45) | PTGS2PPARAPPARDENPP2MAP3K11 | |
| SCHEMBL3893365 | 0.86 | PTGS2 (0.40) | PTGS2PPARAENPP2PPARGPTGES | |
| SCHEMBL3889372 | 0.86 | PPARD (0.44) | PTGS2PPARAPPARDENPP2MAP3K11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |