Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891560 | 0.93 | PTGER1 (0.44) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3891583 | 0.92 | PTGER1 (0.46) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3882813 | 0.90 | MAOB (0.42) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3886465 | 0.90 | PTGS2 (0.43) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3890174 | 0.89 | PTGER1 (0.53) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3886278 | 0.89 | PTGER1 (0.45) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3884238 | 0.89 | PTGER1 (0.52) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3884031 | 0.88 | PTGS2 (0.42) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3883264 | 0.88 | PTGER1 (0.46) | PTGS2PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3886547 | 0.87 | S1PR1 (0.41) | PTGS2PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |