Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16581134 | 0.83 | PARP1 (0.62) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL15228399 | 0.83 | PARP1 (0.62) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL12883029 | 0.83 | PARP1 (0.62) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL27593827 | 0.80 | PARP1 (0.68) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL1164312 | 0.80 | PARP1 (0.68) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL9701377 | 0.80 | PARP1 (0.58) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL28050846 | 0.80 | PARP1 (0.72) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| Hydrochloric Acid SCHEMBL5126803 | 0.79 | PARP1 (0.66) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| Hydrochloric Acid SCHEMBL30615213 | 0.79 | PARP1 (0.66) | PARP1ALDH1A1LMNAALOX12NPC1 | |
| SCHEMBL111826 | 0.78 | PARP1 (0.70) | PARP1ALDH1A1LMNAALOX12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103342698-B | Application of dual-fluorophore ratio fluorescence molecular probe for non-fluorescence resonance energy transfer | UNIV QIQIHAR | 2015-06-17 | — | — | CN | disclosed |
| CN-103342698-A | Dual-fluorophore ratio fluorescence molecular probe for non-fluorescence resonance energy transfer and preparation method thereof | UNIV QIQIHAR | 2013-10-09 | — | — | CN | disclosed |
| CN-101440062-B | Synthesis of N-acyl-8-amino quinoline derivatives and use thereof as fluorescent molecular probe | UNIV QIQIHAR | 2011-09-28 | — | — | CN | disclosed |
| US-7550474-B2 | Substituted phenyl acetamides and their use as protease inhibitors | JOHNSON & JOHNSON PHARMACEUTICALS RESEARCH & DEVELOPMENT, L.L.C. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550474-B2 | Substituted phenyl acetamides and their use as protease inhibitors | JOHNSON & JOHNSON PHARMACEUTICALS RESEARCH & DEVELOPMENT, L.L.C. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550474-B2 | Substituted phenyl acetamides and their use as protease inhibitors | JOHNSON & JOHNSON PHARMACEUTICALS RESEARCH & DEVELOPMENT, L.L.C. (US) | 2009-06-23 | — | — | US | disclosed |
| EP-1613319-B1 | SUBSTITUTED PHENYL ACETAMIDES AND THEIR USE AS PROTEASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1613319-B1 | SUBSTITUTED PHENYL ACETAMIDES AND THEIR USE AS PROTEASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2009-06-03 | — | — | EP | disclosed |
| CN-101440062-A | Synthesis of N-acyl-8-amino quinoline derivatives and use thereof as fluorescent molecular probe | UNIV QIQIHAR (CN) | 2009-05-27 | — | — | CN | disclosed |
| EP-1613319-A2 | SUBSTITUTED PHENYL ACETAMIDES AND THEIR USE AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2006-01-11 | — | — | EP | disclosed |
| US-20040254166-A1 | Substituted phenyl acetamides and their use as protease inhibitors | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, L.L.C. | 2004-12-16 | — | — | US | disclosed |
| WO-2004091613-A2 | SUBSTITUTED PHENYL ACETAMIDES AND THEIR USE AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| WO-2004091613-A2 | SUBSTITUTED PHENYL ACETAMIDES AND THEIR USE AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| EP-0397365-B1 | Arylthiazolylimidazoles as 5HT3 Antagonists | PFIZER (US) | 1994-03-02 | — | — | EP | disclosed |
| EP-0397365-A1 | Arylthiazolylimidazoles as 5HT3 Antagonists | PFIZER INC. (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4914207-A | ANTIEMETICS | PFIZER INC. (US) | 1990-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254166-A1 | Substituted phenyl acetamides and their use as protease inhibitors | TFPI, F12, SPINT2 | PARP1 290/4885ALDH1A1 2539/4885LMNA 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.