Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | NSD2 | O96028 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30513725 | 1.00 | NPC1 (1.00) | NPC1RAB9AMTORSIRT2MEN1 | |
| SCHEMBL29895852 | 1.00 | NPC1 (1.00) | NPC1RAB9AMTORSIRT2MEN1 | |
| SCHEMBL18134578 | 0.93 | NPC1 (0.87) | NPC1RAB9AMTORSIRT2MEN1 | |
| SCHEMBL8650828 | 0.90 | RAB9A (0.82) | NPC1RAB9AMTORSIRT2MEN1 | |
| SCHEMBL7067927 | 0.88 | RAB9A (0.78) | NPC1RAB9AMTORSIRT2MEN1 | |
| SCHEMBL11059596 | 0.87 | RAB9A (0.77) | NPC1RAB9AMTORSIRT2MEN1 | |
| SCHEMBL7064269 | 0.84 | RAB9A (0.72) | NPC1RAB9AMTORSIRT2MEN1 | |
| SCHEMBL7062110 | 0.83 | NPC1 (0.70) | NPC1RAB9AMTORSIRT2MEN1 | |
| SCHEMBL11560999 | 0.80 | NPC1 (0.67) | NPC1RAB9AMTORSIRT2MEN1 | |
| SCHEMBL11172903 | 0.79 | RAB9A (0.66) | NPC1RAB9AMTORSIRT2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014281-A1 | Use of inhibitors of sirtuins and/or ampk for the preparation of a medicament for the treatment of polyalanine diseases. | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-01-14 | — | — | EP | claimed |
| WO-2024143787-A1 | RED PHOTOSENSITIVE RESIN COMPOSITION, COLOR FILTER PREPARED USING SAME, AND SOLID-STATE IMAGING DEVICE OR DISPLAY APPARATUS COMPRISING SAME | 동우 화인켐 주식회사 | 2024-07-04 | — | — | WO | disclosed |
| CN-116643455-A | Colored photosensitive resin composition, color filter produced using the same, and solid-state imaging element or display device comprising the same | 东友精细化工有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-107272339-B | Gray photosensitive resin composition, color filter manufactured using the same, and display element including the color filter | 东友精细化工有限公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-104298075-B | Colored photosensitive resin composition, color filter and display device comprising same | 东友精细化工有限公司 | 2020-12-01 | — | — | CN | disclosed |
| US-10813934-B2 | Sirtuin modulators as inhibitors of cytomegalovirus | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| CN-106019843-B | Colored photosensitive resin composition and color filter manufactured by same | 东友精细化工有限公司 | 2020-07-31 | — | — | CN | disclosed |
| US-20200121620-A1 | SENOLYTIC COMPOUNDS | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2020-04-23 | — | — | US | disclosed |
| US-20200121620-A1 | SENOLYTIC COMPOUNDS | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2020-04-23 | — | — | US | disclosed |
| CN-104950578-B | Colored photosensitive resin composition and color filter produced therefrom | 东友精细化工有限公司 | 2019-12-06 | — | — | CN | disclosed |
| US-20150272939-A1 | Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) and 1B (JARID1B) Histone Demethylase | YALE UNIVERSITY (US) | 2015-10-01 | — | — | US | disclosed |
| US-20150272939-A1 | Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) and 1B (JARID1B) Histone Demethylase | YALE UNIVERSITY (US) | 2015-10-01 | — | — | US | disclosed |
| WO-2012106509-A1 | SIRTUIN MODULATORS AS VIRUS PRODUCTION MODULATORS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-08-09 | — | — | WO | disclosed |
| EP-2014281-A1 | Use of inhibitors of sirtuins and/or ampk for the preparation of a medicament for the treatment of polyalanine diseases. | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-01-14 | — | — | EP | disclosed |
| EP-0797638-B1 | ERASABLE INK COMPOSITION AND MARKING INSTRUMENT CONTAINING SAME | BIC CORP (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-0797638-A1 | ERASABLE INK COMPOSITION AND MARKING INSTRUMENT CONTAINING SAME | BIC CORPORATION (US) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018697-A1 | ERASABLE INK COMPOSITION AND MARKING INSTRUMENT CONTAINING SAME | BIC CORPORATION (US) | 1996-06-20 | — | — | WO | disclosed |
| US-5200290-A | Liquid developers containing colored polymers with a color chromophore covalently bound thereto | XEROX CORPORATION (US) | 1993-04-06 | — | — | US | disclosed |
| US-4778742-A | Colored toner compositions | XEROX CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| US-4645727-A | Colored toner compositions comprising dye chromophores | XEROX CORPORATION (US) | 1987-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10813934-B2 | Sirtuin modulators as inhibitors of cytomegalovirus | SIRT1, SIRT2, SIRT7 | NPC1 2730/4885RAB9A 3558/4885MTOR 358/4885 |
| US-20150272939-A1 | Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) and 1B (JARID1B) Histone Demethylase | KDM1B, KDM1A, JMJD1C | NPC1 4482/4885RAB9A 2177/4885MTOR 2032/4885 |
| US-20200121620-A1 | SENOLYTIC COMPOUNDS | PINK1, PTK2, FYN | NPC1 1637/4885RAB9A 771/4885MTOR 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.