Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23562125 | 0.87 | HRH3 (0.35) | HRH3GABRR1CHRM2CHRM1CHRM3 | |
| SCHEMBL5722384 | 0.83 | SLC6A12 (0.34) | HRH3GABRR1CHRM2CHRM1CHRM3 | |
| SCHEMBL13436048 | 0.82 | CHRNB2 (0.43) | GABRR1GABRR2 | |
| SCHEMBL3547877 | 0.82 | CHRNB2 (0.43) | GABRR1GABRR2 | |
| SCHEMBL13436070 | 0.82 | CHRNB2 (0.43) | GABRR1GABRR2 | |
| SCHEMBL3547882 | 0.82 | CHRNB2 (0.43) | GABRR1GABRR2 | |
| SCHEMBL31368171 | 0.78 | MAPK1 (0.38) | HRH3CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL1298062 | 0.77 | HRH3 (0.43) | HRH3CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL1965621 | 0.75 | CHRM2 (0.48) | HRH3CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL3958434 | 0.75 | CHRM2 (0.48) | HRH3CHRM2CHRM1CHRM3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605169-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2009-10-20 | — | — | US | disclosed |
| US-7605169-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2009-10-20 | — | — | US | disclosed |
| US-7605169-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2009-10-20 | — | — | US | disclosed |
| US-20080009483-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2008-01-10 | — | — | US | disclosed |
| US-20080009483-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2008-01-10 | — | — | US | disclosed |
| US-20080009483-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009483-A1 | Antibacterial Agents | NRDC, NISCH, NAPRT | HRH3 213/4885GABRR1 729/4885CHRM2 3145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.