SCHEMBL3887649

SCHEMBL3887649

CC(O[PH](=O)O)(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
ALOX15 P16050 1/20 0.45
MAPK1 P28482 1/20 0.43
MAPT P10636 2/20 0.42
KMT2A Q03164 1/20 0.42
KCNN4 O15554 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
ESR1 P03372 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2900726 0.86 ALDH1A1 (0.35) ALDH1A1ALOX15MAPK1MAPTKMT2A
SCHEMBL562612 0.85 ALDH1A1 (0.54) ALDH1A1ALOX15MAPK1MAPTKMT2A
SCHEMBL3887648 0.82 MAPK1 (0.46) ALDH1A1ALOX15MAPK1MAPTKMT2A
SCHEMBL6905650 0.80 KCNN4 (0.38) ALDH1A1ALOX15MAPK1MAPTKMT2A
SCHEMBL11850446 0.80 KCNN4 (0.38) ALDH1A1ALOX15MAPK1MAPTKMT2A
SCHEMBL996408 0.79 MAPK1 (0.40) ALDH1A1ALOX15MAPK1MAPTKMT2A
SCHEMBL9818391 0.78 KCNN4 (0.36) ALDH1A1ALOX15MAPK1MAPTKMT2A
SCHEMBL14246478 0.77 PTPN1 (0.42) ALDH1A1ALOX15MAPTKMT2AKCNN4
Tert-Butylbenzene SCHEMBL27531656 0.77 MAPT (0.44) ALDH1A1ALOX15MAPK1MAPTKMT2A
SCHEMBL7129049 0.76 MAPK1 (0.55) ALDH1A1ALOX15MAPK1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed
EP-0644206-B1 Olefin polymerization catalyst and process for preparing polyolefin SHOWA DENKO KK (JP) 1997-12-29 EP disclosed
EP-0644206-A1 Olefin polymerization catalyst and process for preparing polyolefin SHOWA DENKO KABUSHIKI KAISHA (JP) 1995-03-22 EP disclosed
US-5037908-A Process for polymerization of butene-1 TOA NENRYO KOGYO K.K. (JP) 1991-08-06 US disclosed
EP-0201647-B1 PROCESS FOR POLYMERIZATION OF BUTENE-1 Tonen Corporation (JP) 1990-12-27 EP disclosed
EP-0188914-B1 PROCESS FOR COPOLYMERIZATION OF ETHYLENE Tonen Corporation (JP) 1990-12-27 EP disclosed
EP-0201647-A1 Process for polymerization of butene-1 Tonen Corporation (JP) 1986-11-20 EP disclosed
EP-0188914-A2 Process for copolymerization of ethylene Tonen Corporation (JP) 1986-07-30 EP disclosed