Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825910 | 0.89 | CYP19A1 (0.38) | KIF11CYP1A2MAPK1KMT2ACES1 | |
| SCHEMBL8825818 | 0.86 | KIF11 (0.43) | KIF11ALDH1A1KMT2ACES1MEN1 | |
| SCHEMBL3167685 | 0.83 | CRHBP (0.41) | ALDH1A1ALOX15PTPN1MAPK1KMT2A | |
| SCHEMBL11850446 | 0.82 | KCNN4 (0.38) | KCNN4ALDH1A1CYP1A2ALOX15PTPN1 | |
| SCHEMBL6905649 | 0.81 | KIF11 (0.40) | KCNN4KIF11ALDH1A1CYP1A2ALOX15 | |
| SCHEMBL5204429 | 0.80 | MEN1 (0.40) | ALDH1A1CYP1A2ALOX15PTPN1KMT2A | |
| SCHEMBL9818391 | 0.80 | KCNN4 (0.36) | KCNN4ALDH1A1CYP1A2ALOX15PTPN1 | |
| SCHEMBL3887649 | 0.80 | ALDH1A1 (0.45) | KCNN4ALDH1A1CYP1A2ALOX15PTPN1 | |
| SCHEMBL3178203 | 0.79 | — | — | |
| SCHEMBL11610528 | 0.79 | GABRA1 (0.36) | KCNN4KIF11ALDH1A1ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489380-A | Phosphorous containing compounds including triphenylmethylphosphonate esters for the treatment of melanoma and other cancers | UNIV ILLINOIS (US) | 2009-07-22 | — | — | CN | disclosed |
| US-20040044168-A1 | Phosphorus- and nitrogen-containing resin hardener and a flame retarding resin composition containing said hardener | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-03-04 | — | — | US | disclosed |
| US-6617028-B1 | Oxaphosphophenanthranene-substituted melamines or diaminotriazines; epoxy resins | CHANG CHUN PLASTICS CO., LTD. (TW) | 2003-09-09 | — | — | US | disclosed |
| US-5786401-A | CONCURRENT BLOWING, MOLDING OF POLYURETHANE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| US-5741825-A | CLOSED CELL FOAM FOR HEAT RESISTANCE FORMED BY BLOWING WITH IODOFLUOROHYDROCARBONS AND HYDROGEN CONTAINING FLUOROMORPHOLINE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| EP-0700953-A2 | Thermal insulating foamed material and method for manufacturing the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1996-03-13 | — | — | EP | disclosed |