Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | PPARA | Q07869 | 11/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 5/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883672 | 0.91 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL3882409 | 0.88 | PTGER1 (0.42) | PPARGPPARAC5AR1PPARDPLA2G10 | |
| SCHEMBL3882927 | 0.86 | PPARG (0.44) | PPARGPPARAC5AR1PPARDPLA2G10 | |
| SCHEMBL3889302 | 0.85 | PPARG (0.46) | PPARGPPARAPPARDPLA2G10PLA2G2A | |
| SCHEMBL3682912 | 0.83 | THRA (0.46) | PPARAC5AR1PPARD | |
| SCHEMBL3883278 | 0.82 | C5AR1 (0.41) | PPARGPPARAC5AR1PPARDKEAP1 | |
| SCHEMBL3888439 | 0.82 | FFAR4 (0.54) | PPARAC5AR1PPARD | |
| SCHEMBL3888367 | 0.81 | PDE4B (0.44) | PPARGPPARAPPARDKEAP1NFE2L2 | |
| SCHEMBL3883274 | 0.81 | FFAR4 (0.55) | PPARAC5AR1PPARD | |
| SCHEMBL3882136 | 0.80 | PPARG (0.41) | PPARGPPARAC5AR1PPARDPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |