Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889242 | 1.00 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1MAPTGFEREGFR | |
| SCHEMBL19305994 | 0.87 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1MAPTGFEREGFR | |
| SCHEMBL12013236 | 0.86 | GFER (0.68) | L3MBTL1ALDH1A1MAPTGFEREGFR | |
| SCHEMBL28037508 | 0.86 | GFER (0.68) | L3MBTL1ALDH1A1MAPTGFEREGFR | |
| SCHEMBL27898212 | 0.82 | GFER (0.63) | L3MBTL1ALDH1A1MAPTGFERHPGD | |
| SCHEMBL27915949 | 0.78 | GFER (0.55) | L3MBTL1ALDH1A1MAPTGFERHPGD | |
| SCHEMBL944348 | 0.78 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1MAPTGFEREGFR | |
| SCHEMBL944350 | 0.78 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1MAPTGFEREGFR | |
| SCHEMBL27806241 | 0.74 | GAA (0.70) | L3MBTL1ALDH1A1MAPTMAPK1MEN1 | |
| SCHEMBL31310377 | 0.73 | CA2 (0.64) | L3MBTL1ALDH1A1MAPTGFERMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252940-B2 | 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection | UNIVERSITY OF WASHINGTON (US) | 2012-08-28 | — | — | US | disclosed |
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |