Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12013236 | 1.00 | GFER (0.68) | GFERALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL27898212 | 0.90 | GFER (0.63) | GFERALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL3889242 | 0.86 | L3MBTL1 (0.64) | GFERALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL3889245 | 0.86 | L3MBTL1 (0.64) | GFERALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL27915949 | 0.85 | GFER (0.55) | GFERALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL31310377 | 0.85 | CA2 (0.64) | GFERALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL945891 | 0.81 | ALDH1A1 (0.58) | GFERALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL945889 | 0.81 | ALDH1A1 (0.58) | GFERALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28177739 | 0.78 | CA9 (0.56) | GFERALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL2589792 | 0.78 | MEN1 (0.68) | GFERALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961707-B | Substituted thiazole ketone secretory protease inhibitors and preparation method thereof | 中国人民解放军第二军医大学 | 2017-07-28 | — | — | CN | disclosed |
| CN-104961707-A | Substituted thiazole ketones secretory aspartic protease inhibitor and preparation thereof | UNIV PLA 2ND MILITARY MEDICAL | 2015-10-07 | — | — | CN | disclosed |