Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 9/20 | 0.35 |
| ▸ | CA2 | P00918 | 9/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889588 | 1.00 | KMT2A (0.41) | KMT2AGAALMNAHPGDSMN1; SMN2 | |
| SCHEMBL1259649 | 0.80 | KMT2A (0.46) | KMT2AGAALMNAHPGDSMN1; SMN2 | |
| SCHEMBL1259646 | 0.80 | KMT2A (0.46) | KMT2AGAALMNAHPGDSMN1; SMN2 | |
| SCHEMBL1259391 | 0.78 | KMT2A (0.43) | KMT2AGAALMNAHPGDSMN1; SMN2 | |
| SCHEMBL1259326 | 0.78 | KMT2A (0.43) | KMT2AGAALMNAHPGDSMN1; SMN2 | |
| SCHEMBL1259321 | 0.78 | KMT2A (0.43) | KMT2AGAALMNAHPGDSMN1; SMN2 | |
| SCHEMBL3956384 | 0.74 | KMT2A (0.41) | KMT2AGAACA1CA2 | |
| SCHEMBL3956382 | 0.74 | KMT2A (0.41) | KMT2AGAACA1CA2 | |
| SCHEMBL3893609 | 0.73 | NOS3 (0.32) | — | |
| SCHEMBL3893611 | 0.73 | NOS3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |