Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893611 | 1.00 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL6670962 | 0.75 | GABRP (0.41) | NOS3NOS1NOS2 | |
| SCHEMBL2495115 | 0.75 | NOS2 (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL3889575 | 0.73 | KMT2A (0.41) | — | |
| SCHEMBL3889588 | 0.73 | KMT2A (0.41) | — | |
| SCHEMBL1257531 | 0.69 | NOS2 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL1257530 | 0.69 | NOS2 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL6245968 | 0.69 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL1852682 | 0.69 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL6665323 | 0.69 | ALDH1A1 (0.35) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |