SCHEMBL3890397

SCHEMBL3890397

CC(C)CO[Si](CC(C)C)(CC(C)C)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
MAOA P21397 1/20 0.36
PTGS1 P23219 1/20 0.36
HPGD P15428 2/20 0.34
MAPT P10636 2/20 0.34
POLB P06746 1/20 0.34
XBP1 P17861 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
MTNR1A P48039 3/20 0.33
MTNR1B P49286 3/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
CYP2D6 P10635 1/20 0.33
ADRB3 P13945 1/20 0.33
ELANE P08246 1/20 0.32
MEN1 O00255 1/20 0.32
ALOX12 P18054 1/20 0.32
KMT2A Q03164 1/20 0.32
CA4 P22748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5029806 0.87 LMNA (0.41) LMNAMAOAPTGS1MAPTPOLB
SCHEMBL5031085 0.79 LMNA (0.42) LMNAMAOAPTGS1HPGDMAPT
SCHEMBL5034155 0.79 LMNA (0.42) LMNAMAOAPTGS1HPGDMAPT
SCHEMBL5027517 0.79 LMNA (0.42) LMNAMAOAPTGS1HPGDMAPT
SCHEMBL5029859 0.76 LMNA (0.40) LMNAMAOAPTGS1HPGDMAPT
SCHEMBL2398631 0.75 LMNA (0.41) LMNAMAOAPTGS1POLBTSHR
SCHEMBL2959575 0.73 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL9697307 0.73 LMNA (0.39) LMNAMAOAPTGS1TSHRMTNR1A
SCHEMBL3890394 0.70 ALDH1A1 (0.35) LMNAMAOAPTGS1HPGDMAPT
SCHEMBL18270226 0.70 ALDH1A1 (0.35) LMNAMAOAPTGS1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed