SCHEMBL9697307

SCHEMBL9697307

CC(C)C[Si](C)(C)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
MAOA P21397 1/20 0.36
PTGS1 P23219 1/20 0.36
CA4 P22748 1/20 0.36
ANPEP P15144 1/20 0.34
LAP3 P28838 1/20 0.34
LTA4H P09960 2/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.33
KCNA3 P22001 1/20 0.33
METAP2 P50579 1/20 0.33
METAP1 P53582 1/20 0.33
MTNR1A P48039 4/20 0.33
MTNR1B P49286 4/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
CYP2D6 P10635 1/20 0.33
ADRB3 P13945 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2398631 0.81 LMNA (0.41) LMNAMAOAPTGS1CA4ANPEP
SCHEMBL5029806 0.81 LMNA (0.41) LMNAMAOAPTGS1CA4ANPEP
SCHEMBL6235956 0.80
SCHEMBL6236758 0.80 MAPT (0.35) LMNAMAOAKDM4E
SCHEMBL6236737 0.78 MAOB (0.41) LMNAMAOAKDM4E
SCHEMBL6243945 0.78 TAAR1 (0.33)
SCHEMBL710740 0.78 CA4 (0.42) LMNACA4LTA4HTSHRKCNA3
SCHEMBL707221 0.78 CA4 (0.42) LMNACA4LTA4HTSHRKCNA3
SCHEMBL19816761 0.76 LTA4H (0.40) LMNACA4LTA4HTSHRKDM4E
SCHEMBL13089242 0.75 LMNA (0.36) LMNAMAOAPTGS1CA4LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5080971-A Durable, weatherproof, wear and corrosion resistant TDK CORPORATION (JP) 1992-01-14 US disclosed
US-5069967-A Durability, thin metal film. plasma polymerized film, fluoropo lymer film TDK CORPORATION (JP) 1991-12-03 US disclosed
US-4988573-A MAGNETIC RECORDING MEDIA, PLASMA POLYMERIZED FILM ON A SURFACE SUCH AS A TAPE OR DISK TDK CORPORATION (JP) 1991-01-29 US disclosed