Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886882 | 0.84 | FGFR1 (0.56) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL13937651 | 0.81 | MAPT (0.38) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL10968807 | 0.72 | MAPT (0.50) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL3904565 | 0.69 | FGFR1 (0.61) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL9878296 | 0.67 | ELANE (0.60) | MAPTKDM4ERECQLMEN1KMT2A | |
| SCHEMBL10967826 | 0.66 | MAPT (0.62) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL10970754 | 0.66 | MAPT (0.48) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL143878 | 0.66 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL13937653 | 0.66 | FGFR1 (0.54) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL8996338 | 0.64 | MEN1 (0.55) | FGFR1FGFR2FGFR4FGFR3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019616-A2 | ISOPREKINAMYCIN ANALOGS AND SYNTHESES THEREOF | UNIVERSITY OF MANITOBA (US) | 2009-02-12 | — | — | WO | disclosed |